Structure and Dynamics of Confined Polymers

  • John J. Kasianowicz
  • Miklós S. Z. Kellermayer
  • David W. Deamer

Part of the NATO Science Series book series (ASHT, volume 87)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Lucienne Letellier
    Pages 23-36
  3. Stephan Nussberger, Walter Neupert
    Pages 67-84
  4. Kathleen W. Kinnally
    Pages 85-95
  5. O. V. Krasilnikov
    Pages 97-115
  6. Sergey M. Bezrukov, John J. Kasianowicz
    Pages 117-130
  7. C. Gay, P.-G. de Gennes, E. Raphaël, F. Brochard-Wyart
    Pages 131-139
  8. John J. Kasianowicz, Sarah E. Henrickson, Martin Misakian, Howard H. Weetall, Baldwin Robertson, Vincent Stanford
    Pages 141-163
  9. David W. Deamer, Hugh Olsen, Mark A. Akeson, John J. Kasianowicz
    Pages 165-175
  10. Daniel Branton, Amit Meller
    Pages 177-185
  11. Mark Akeson, David W. Deamer, Wenonah Vercoutere, Rebecca Braslau, Hugh Olsen
    Pages 187-200
  12. Björn Åkerman
    Pages 201-225
  13. Murugappan Muthukumar
    Pages 227-239
  14. Wokyung Sung, Pyeong Jun Park
    Pages 261-280
  15. Miklós S. Z. Kellermayer, Steven Smith, Carlos Bustamante, Henk L. Granzier
    Pages 311-326

About these proceedings

Introduction

Polymers are essential to biology because they can have enough stable degrees of freedom to store the molecular code of heredity and to express the sequences needed to manufacture new molecules. Through these they perform or control virtually every function in life. Although some biopolymers are created and spend their entire career in the relatively large free space inside cells or organelles, many biopolymers must migrate through a narrow passageway to get to their targeted destination. This suggests the questions: How does confining a polymer affect its behavior and function? What does that tell us about the interactions between the monomers that comprise the polymer and the molecules that confine it? Can we design and build devices that mimic the functions of these nanoscale systems? The NATO Advanced Research Workshop brought together for four days in Bikal, Hungary over forty experts in experimental and theoretical biophysics, molecular biology, biophysical chemistry, and biochemistry interested in these questions. Their papers collected in this book provide insight on biological processes involving confinement and form a basis for new biotechnological applications using polymers. In his paper Edmund DiMarzio asks: What is so special about polymers? Why are polymers so prevalent in living things? The chemist says the reason is that a protein made of N amino acids can have any of 20 different kinds at each position along the chain, resulting in 20 N different polymers, and that the complexity of life lies in this variety.

Keywords

Biophysics Copolymer DNA Nucleotide REM STEM fluorescence polymer proteins

Editors and affiliations

  • John J. Kasianowicz
    • 1
  • Miklós S. Z. Kellermayer
    • 2
  • David W. Deamer
    • 3
  1. 1.Biotechnology DivisionNational Institute of Standards and TechnologyGaithersburgUSA
  2. 2.Department of BiophysicsPécs University Medical SchoolPécsHungary
  3. 3.Biophysics Laboratory, Department of Chemistry and BiochemistryUniversity of CaliforniaSanta CruzUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-010-0401-5
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4020-0698-2
  • Online ISBN 978-94-010-0401-5
  • Series Print ISSN 1388-6576
  • About this book