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Mechanics of Elastic Biomolecules

  • Wolfgang A. Linke
  • Henk Granzier
  • Miklós S. Z. Kellermayer

Table of contents

  1. Front Matter
    Pages i-vii
  2. DNA, Chromatin and Chromosomes

    1. Front Matter
      Pages 365-365
    2. M. Hegner, W. Grange
      Pages 367-375
    3. Jordanka Zlatanova, Sanford H. Leuba
      Pages 377-395
    4. Lisa H. Pope, Martin L. Bennink, Jan Greve
      Pages 397-407
    5. M. G. Poirier, J. F. Marko
      Pages 409-431
  3. Elastic Invertebrate Muscle Proteins

    1. Front Matter
      Pages 433-433
    2. Belinda Bullard, Wolfgang A. Linke, Kevin Leonard
      Pages 435-447
  4. The Elastic Vertebrate Muscle Protein Titin

  5. Cytoskeletal Proteins

    1. Front Matter
      Pages 523-523
    2. Ning Wang, Dimitrijie Stamenovic
      Pages 535-540
  6. Extracellular Matrix Proteins

    1. Front Matter
      Pages 541-541
    2. Bin Li, Valerie Daggett
      Pages 561-573
    3. Harold P. Erickson
      Pages 575-580
    4. C. M. Kielty, T. J. Wess, L. Haston, Jane L. Ashworth, M. J. Sherratt, C. A. Shuttleworth
      Pages 581-596

About this book

Introduction

A representative cross-section of elastic biomolecules is covered in this volume, which combines seventeen contributions from leading research groups. State-of-the-art molecular mechanics experiments are described dealing with the elasticity of DNA and nucleoprotein complexes, titin and titin-like proteins in muscle, as well as proteins of the cytoskeleton and the extracellular matrix.
The book speaks particularly to cell biologists, biophysicists, or bioengineers, and to senior researchers and graduate students alike, who are interested in recent advances in single-molecule technology (optical tweezers technique, atomic force microscopy), EM imaging, and computer simulation approaches to study nanobiomechanics. The findings discussed here have redefined our view of the role mechanical signals play in cellular functions and have greatly helped improve our understanding of biological elasticity in general.

Keywords

DNA Glutamat biomechanics pathophysiology physiology protein complexes proteins

Editors and affiliations

  • Wolfgang A. Linke
    • 1
  • Henk Granzier
    • 2
  • Miklós S. Z. Kellermayer
    • 3
  1. 1.University of HeidelbergHeidelbergGermany
  2. 2.Washington State UniversityPullmanUSA
  3. 3.University of PécsPécsHungary

Bibliographic information

Industry Sectors
Pharma
Biotechnology