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Future Aspects in Contraception

Proceeding of an International Symposium held in Heidelberg, 5–8 September 1984 Part 1 Male Contraception

  • B. Runnebaum
  • T. Rabe
  • Ludwig Kiesel

Table of contents

  1. Front Matter
    Pages i-x
  2. T. Rabe, L. Kiesel, B. Runnebaum
    Pages 1-127
  3. K.-W. Von Eickstedt
    Pages 145-152
  4. H. Kuhl, H.-J. Born, M. Schneider, J. Sandow, W. Singer, H.-D. Taubert
    Pages 153-166
  5. T. J. Lobl, G. R. Cunningham, J. A. Campbell, D. J. Tindall
    Pages 167-178
  6. A. Belanger, F. Labrie, Y. Tremblay, A. Dupont, R. St-Arnaud
    Pages 179-189
  7. N. R. Farnsworthv, A. S. Bingel
    Pages 205-218
  8. G.-Z. Liu
    Pages 229-236
  9. S. A. Matlin, R. H. Zhou
    Pages 237-241
  10. Back Matter
    Pages 267-270

About this book

Introduction

Atrophy of gonadotrophin producing cells Exogenously LH synthesis administered androgens and release or anabolic steroids are decreased Prostate Testes Normal function. Testosterone synthesis in The deficit of endogenously Leydig cells is decreased. The synthesized testosterone is exogenously administered compensated for by the steroid is not able to exogenously administered compensate for the deficit of steroid endogenously synthesized testosterone Figure 2 Intratesticular and serum testosterone concentrations after treatment with andro­ gens or anabolic steroids in order to substitute for the peripheral androgen deficiency and to achieve azoospermia. Because this steroid is alkylated in position 17, toxic effects on liver function can not be excluded. Danazol offers no advantages as compared with other anabolic steroids; rather, disadvantages. Numerous experiments of this type have been performed during the last 40 or 50 years. The outcome in each case was more or less identical: with a certain dose of an androgen or anabolic steroid it is possible to inhibit spermatogenesis without interfering with other androgen-dependent func­ tions, including libido (potentia coeundi) and accessory sexual glands. On the basis of this pharmacological-endocrinological background, androgens and anabolic steroids can be used for male fertility control, and several clinical trials have been performed during the last 10-15 years. Some of 1 these studies 2-23 are mentioned in Table 2.

Keywords

birth contraception fertility hormones

Editors and affiliations

  • B. Runnebaum
    • 1
  • T. Rabe
    • 1
  • Ludwig Kiesel
    • 1
  1. 1.Division of Gynaecological Endocrinology, Department of Obstetrics and GynaecologyUniversity of HeidelbergHeidelberg 1West Germany

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-4910-2
  • Copyright Information Springer Science+Business Media B.V. 1985
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-8675-2
  • Online ISBN 978-94-009-4910-2
  • Buy this book on publisher's site
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