Advertisement

Laboratory Animals in Vaccine Production and Control

Replacement, reduction and refinement

  • Coenraad F. M. Hendriksen

Part of the Developements in Hematology and Immunology book series (DIHI, volume 20)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Coenraad F. M. Hendriksen
    Pages 1-2
  3. Coenraad F. M. Hendriksen
    Pages 23-35
  4. Coenraad F. M. Hendriksen
    Pages 37-49
  5. Coenraad F. M. Hendriksen
    Pages 51-55
  6. Coenraad F. M. Hendriksen
    Pages 57-62
  7. Coenraad F. M. Hendriksen
    Pages 139-144
  8. Coenraad F. M. Hendriksen
    Pages 145-149
  9. Coenraad F. M. Hendriksen
    Pages 151-157
  10. Back Matter
    Pages 158-158

About this book

Introduction

9. REFERENCES 90 CHAPTER 9: OPPORTUNITIES FOR REPLACEMENT, REDUCTION AND REFINEMENT: HUMAN VIRAL VACCINES 93 1. INTRODUCTION 93 2. TESTS FOR EXTRANEOUS MICROORGANISMS 94 3. MUMPS VACCINE . . . 94 4. HEPATITIS B VACCINE 95 4. 1. Test for freedom from live hepatitis virus 95 4. 2. Potency test 95 5. INFLUENZA VACCINE 96 5. 1. Potency test 96 5. 2. Abnormal-toxicity test 96 6. MEASLES VACCINE. . . . . 96 6. 1. Tests for extraneous agents 97 6. 1. 1. Test for Mycobacterium tuberculosis 97 6. 1. 2. Test for extraneous viruses 97 6. 2. Abnormal-toxicity test 98 7. POLIOMYELITIS VACCINE. . . 99 7. A. Inactivated poliomyelitis vaccine 99 7. A. l. Production. . . . . . 99 7. A. 2. Test for residual live virus 99 7. A. 3. Tests for extraneous agents 100 7. A. 3. l. Test for Mycobacterium tuberculosis . . . . . 100 7. A. 3. 2. Test for extraneous viruses 100 7. A. 4. Tumourigenicity test. . . . . 100 XII 7 . A. 5. Potency test . . . . . . . 101 7. A. 6. Test for abnormal toxicity 102 7. B. Live, oral poliomyelitis vaccine 103 7. B. l. Test for extraneous agents 103 7. B. 2. Test for neurovirulence 105 7. B. 3. Test for abnormal toxicity 106 8. RABIES VACCINE 106 8. 1. Production 106 8. 2. Test for residual live virus 107 8. 3. Tests for extraneous microorganisms 107 8. 3. 1. Test for Mycobacterium tuberculosis 107 8. 3. 2. Tests for extraneous viruses 108 8. 3. 2. 1. In dogs 108 8. 3. 2. 2.

Keywords

Laboratory vaccine

Authors and affiliations

  • Coenraad F. M. Hendriksen
    • 1
  1. 1.National Institute of Public Health and Environmental ProtectionThe Netherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-1321-9
  • Copyright Information Springer Science+Business Media B.V. 1988
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-7088-1
  • Online ISBN 978-94-009-1321-9
  • Buy this book on publisher's site
Industry Sectors
Pharma
Biotechnology
Consumer Packaged Goods