Improving Genetic Disease Resistance in Farm Animals

  • A. J. Van Der Zijpp
  • W. Sybesma

Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 52)

Table of contents

  1. Front Matter
    Pages i-viii
  2. General Aspects

    1. Front Matter
      Pages 1-1
    2. A. J. van der Zijpp
      Pages 3-5
    3. R. R. P. de Vries
      Pages 6-12
  3. MHC serology and immunology

    1. Front Matter
      Pages 13-13
    2. R. L. Spooner, R. A. Oliver, E. J. Glass, E. A. Innes
      Pages 15-22
    3. Birte Kristensen
      Pages 23-32
    4. H. Varewyck, Y. Bouquet
      Pages 33-41
    5. M. Simonsen, M. Arnul, P. Sørensen
      Pages 42-62
    6. E. Egberts, R. J. M. Stet, P. Kaastrup, C. N. Pourreau, W. B. van Muiswinkel
      Pages 63-71
  4. MHC polymorphism by protein chemistry and DNA techniques

    1. Front Matter
      Pages 73-73
    2. E. J. Hensen, I. Joosten, A. van de Poel, M. F. Sanders
      Pages 75-80
    3. J. L. Williams, P. Brown, E. J. Glass, R. A. Oliver, R. L. Spooner
      Pages 81-90
    4. Patrick Chardon
      Pages 91-98
  5. Sessions 4 MHC and disease associations Chairpersons: Dr. M. Vaiman and Dr. S. Lazary

About this book


This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics". The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.


anatomy animals development genetics system

Authors and affiliations

  • A. J. Van Der Zijpp
    • 1
  • W. Sybesma
    • 2
  1. 1.Department of Animal HusbandryAgricultural UniversityWageningenThe Netherlands
  2. 2.Reasearch Institute for Animal Production ‘Schoonoord’ZeistThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1989
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6967-0
  • Online ISBN 978-94-009-1057-7
  • About this book
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