Regenerative Medicine

1. Front Matter

   Pages i-xxi

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2. History of Regenerative Medicine

   • Raymund E. Horch, Laurentiu M. Popescu, Elias Polykandriotis

   Pages 1-17

3. Biology of Tissue Regeneration

   1. Front Matter

      Pages 19-19

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   2. Extracellular Matrix and Tissue Regeneration

      • Yrjö T. Konttinen, Emilia Kaivosoja, Vasily Stegaev, Hanoch Daniel Wagner, Jaakko Levón, Veli-Matti Tiainen et al.

      Pages 21-78

   3. Stem Cell Niche

      • Chenhui Wang, Pei Wen, Pei Sun, Rongwen Xi

      Pages 79-106

   4. Stem Cells and Asymmetric Cell Division

      • Frank Hirth

      Pages 107-127

   5. Stem Cells in the Developing and Adult Nervous System

      • Fumitaka Osakada, Masayo Takahashi

      Pages 129-152

4. Stem Cell Science and Technology

   1. Front Matter

      Pages 153-153

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   2. Characterization and Classification of Stem Cells

      • Ute Bissels, Dominik Eckardt, Andreas Bosio

      Pages 155-176

   3. Human Embryonic Stem Cells

      • Mikael C. O. Englund, Peter Sartipy, Johan Hyllner

      Pages 177-196

   4. Induced Pluripotent Stem Cells

      • Keisuke Okita, Kazutoshi Takahashi, Shinya Yamanaka

      Pages 197-218

   5. Spermatogonial Stem Cells

      • Ilya Chuykin, Michael Stauske, Kaomei Guan

      Pages 219-249

   6. Hematopoietic Stem Cells

      • Mary L. Clarke, Jonathan Frampton

      Pages 251-277

   7. Cardiovascular Stem Cells

      • Christoph Brenner, Robert David, Wolfgang-Michael Franz

      Pages 279-295

   8. Neural Stem Cells

      • Yoko Arai, Wieland B. Huttner, Federico Calegari

      Pages 297-335

   9. Liver Stem Cells

      • Tohru Itoh, Hinako Takase, Minoru Tanaka, Atsushi Miyajima

      Pages 337-363

   10. Gastro Intestinal Stem Cells

       • M. Sasikala, G. V. Rao, Manu Tandan, D. Nageshwar Reddy

       Pages 365-385

   11. Cancer Stem Cells

       • Murali M. S. Balla, Anjali P. Kusumbe, Geeta K. Vemuganti, Sharmila A. Bapat

       Pages 387-412

   12. Mesenchymal Stem Cells – An Oversimplified Nomenclature for Extremely Heterogeneous Progenitors

       • Patrick Wuchter, Wolfgang Wagner, Anthony D. Ho

       Pages 413-431

   13. Musculoskeletal Stem Cells

       • Gerben M. van Buul, Gerjo J. V. M. van Osch

       Pages 433-453

The field of regenerative medicine has developed rapidly over the past 20 years with the advent of molecular and cellular techniques. This textbook,  Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from four continents describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This textbook is organized into five parts: (I) Biology of Tissue Regeneration, (II) Stem Cell Science and Technology, (III) Tissue Engineering, Biomaterials and Nanotechnology, (IV) Regenerative Therapies and (V) Regulation and Ethics. The textbook aims to give the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.

• Biomaterials
• Regenerative medicine
• Stem cell research
• Stem cell therapy
• Tissue Engineering

From the reviews of the second edition:

“It is intended for students, research scientists, physicians, and other healthcare professionals. The general audience, especially potential patients, should also find this book informative. … This book offers broad coverage of the fast emerging and extremely diverse field of research and clinical therapies in regenerative medicine. This updated edition provides a comprehensive overview of the state-of-the-art scientific and clinical knowledge in the field.” (Joanna Goral, Doody’s Book Reviews, January, 2014)

• Klinik und Poliklinik für Herzchirurgie, Universitätsklinikum Rostock, Rostock, Germany

  Gustav Steinhoff

Policies and ethics