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Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2

Statistics on a Pocket Calculator, Part 2

  • Ton J. Cleophas
  • Aeilko H. Zwinderman

Part of the SpringerBriefs in Statistics book series (BRIEFSSTATIST)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 1-2
  3. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 3-5
  4. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 7-10
  5. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 11-13
  6. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 21-22
  7. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 23-25
  8. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 27-30
  9. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 31-33
  10. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 35-40
  11. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 41-44
  12. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 45-47
  13. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 49-52
  14. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 53-54
  15. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 55-56
  16. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 57-59
  17. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 61-62
  18. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 63-64
  19. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 65-68
  20. Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 69-71
  21. Back Matter
    Pages 73-78

About this book

Introduction

The first part of this title contained all statistical tests relevant to starting clinical investigations, and included tests for continuous and binary data, power, sample size, multiple testing, variability, confounding, interaction, and reliability. The current part 2 of this title reviews methods for handling missing data, manipulated data, multiple confounders, predictions beyond observation, uncertainty of diagnostic tests, and the problems of outliers. Also robust tests, non-linear modeling , goodness of fit testing, Bhatacharya models, item response modeling, superiority testing, variability testing, binary partitioning for CART (classification and regression tree) methods, meta-analysis, and simple tests for incident analysis and unexpected observations at the workplace and reviewed.

Each test method is reported together with (1) a data example from practice, (2) all steps to be taken using a scientific pocket calculator, and (3) the main results and their interpretation. Although several of the described methods can also be carried out with the help of statistical software, the latter procedure will be considerably slower.

Both part 1 and 2 of this title consist of a minimum of text and this will enhance the process of mastering the methods. Yet the authors recommend that for a better understanding of the test procedures the books be used together with the same authors' textbook "Statistics Applied to Clinical Studies" 5th edition edited 2012, by Springer Dordrecht Netherlands. More complex data files like data files with multiple treatment modalities or multiple predictor variables can not be analyzed with a pocket calculator. We recommend that the small books "SPSS for starters", Part 1 and 2 (Springer, Dordrecht, 2010, and 2012) from the same authors be used as a complementary help for the readers' benefit.

Keywords

Clinical data analysis Computer science Data management Data mining Machine learning

Authors and affiliations

  • Ton J. Cleophas
    • 1
  • Aeilko H. Zwinderman
    • 2
  1. 1.SliedrechtNetherlands
  2. 2.LeidenNetherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-4704-3
  • Copyright Information The Author(s) 2012
  • Publisher Name Springer, Dordrecht
  • eBook Packages Mathematics and Statistics
  • Print ISBN 978-94-007-4703-6
  • Online ISBN 978-94-007-4704-3
  • Series Print ISSN 2191-544X
  • Series Online ISSN 2191-5458
  • Buy this book on publisher's site
Industry Sectors
Pharma
Health & Hospitals
Biotechnology