Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

  • Rudolf Toman
  • Robert A. Heinzen
  • James E. Samuel
  • Jean-Louis Mege

Part of the Advances in Experimental Medicine and Biology book series (volume 984)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Erin J. van Schaik, James E. Samuel
    Pages 13-38
  3. Craig T. Narasaki, Rudolf Toman
    Pages 65-90
  4. Guoquan Zhang, Yan Zhang, James E. Samuel
    Pages 91-104
  5. Robert Ihnatko, Edward Shaw, Rudolf Toman
    Pages 105-130
  6. S. Kauser Hussain, Daniel E. Voth
    Pages 131-140
  7. Eric Ghigo, María I. Colombo, Robert A. Heinzen
    Pages 141-169
  8. Justin A. McDonough, Hayley J. Newton, Craig R. Roy
    Pages 171-197
  9. Stacey D. Gilk
    Pages 199-213
  10. Anders Omsland
    Pages 215-229
  11. Michael F. Minnick, Rahul Raghavan
    Pages 231-248
  12. Paul A. Beare
    Pages 249-271
  13. Christian Capo, Jean-Louis Mege
    Pages 273-286
  14. Amira Ben Amara, Yassina Bechah, Jean-Louis Mege
    Pages 287-298
  15. Laura R. Hendrix, Chen Chen
    Pages 299-328
  16. Wim van der Hoek, Gabriëlla Morroy, Nicole H. M. Renders, Peter C. Wever, Mirjam H. A. Hermans, Alexander C. A. P. Leenders et al.
    Pages 329-364
  17. Jianmin Zhong
    Pages 365-379
  18. Robert F. Massung, Sally J. Cutler, Dimitrios Frangoulidis
    Pages 381-396

About this book

Introduction

Over 20 years have elapsed since publication of the seminal two volume series entitled Q Fever: The Biology of Coxiella burnetii (edited by J. C. Williams and H. A. Thompson) and Q fever: The Disease (edited by T. J. Marrie) that described the current state of Coxiella burnetii research. The ensuing years have brought the post-genomic era and accompanying technologies that have catalyzed major advances in the field, including milestones discoveries of genetic transformation and host cell-free growth of this former obligate intracellular bacterium. Understanding how the bacterium resists the degradative functions of vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen.  

The book covers the current state-of-the-art knowledge in the selected fields of C. burnetii/Q fever research. Coxiella has matured from a niche organism, investigated by a handful of laboratories worldwide, to a model system to study macrophage parasitism, developmental biology, host-pathogen interactions, and immune evasion/modulation.

Keywords

Coxiella burnetii Developmental biology Host-pathogen interactions Immune evasion/modulation Q fever

Editors and affiliations

  • Rudolf Toman
    • 1
  • Robert A. Heinzen
    • 2
  • James E. Samuel
    • 3
  • Jean-Louis Mege
    • 4
  1. 1.Institute of Virology, Dept. of RickettsiologySlovak Academy of SciencesBratislavaSlovakia
  2. 2.Rocky Mountain Laboratories, Coxiella Pathogenesis SectionNIH/NIAIDHamiltonUSA
  3. 3., Microbial and Molecular PathogenesisCollege of Medicine, Texas A&MCollege StationUSA
  4. 4.Institut Fédératif de Recherche 48, Les Maladies Infect TransmissiblesCNRS-IRD UMR 6236Marseille, Cedex 05France

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-4315-1
  • Copyright Information Springer Science+Business Media Dordrecht 2012
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-4314-4
  • Online ISBN 978-94-007-4315-1
  • Series Print ISSN 0065-2598
  • About this book
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