Advertisement

Midkine: From Embryogenesis to Pathogenesis and Therapy

  • Mine Ergüven
  • Takashi Muramatsu
  • Ayhan Bilir

Table of contents

  1. Front Matter
    Pages i-ix
  2. General Aspects of Midkine

    1. Front Matter
      Pages 1-1
    2. Takashi Muramatsu
      Pages 3-13
    3. Sheng Yao, Christoph Winkler
      Pages 15-28
    4. Sara L. Nordin, Arne Egesten
      Pages 29-39
    5. Yiping Huang, Edward A. Ratovitski
      Pages 41-52
    6. Stefan Sommerschuh, Michael Kirchner, Nicole Gliese
      Pages 53-67
    7. Malgorzata Krzystek-Korpacka, Malgorzata Matusiewicz
      Pages 69-85
  3. Midkine and Inflammation

    1. Front Matter
      Pages 87-87
    2. Nuray Yazıhan, Mehtap Kacar Kocak, Ethem Akcıl
      Pages 89-101
    3. Hisako Muramatsu, Kiyoko Maruyama, Naoki Ishiguro
      Pages 103-109
  4. Midkine and the Cardiovascular System

    1. Front Matter
      Pages 111-111
    2. Mitsuru Horiba, Kenji Kadomatsu
      Pages 113-124
    3. Kenji Kadomatsu
      Pages 125-130
    4. Tomoki Kosugi, Kenji Kadomatsu
      Pages 131-140
  5. Midkine and the Nervous System

    1. Front Matter
      Pages 141-141
    2. Hideyuki Takeuchi
      Pages 143-151
    3. Hiroaki Ooboshi, Eiichi Ishikawa, Junichi Takada, Takashi Shichita, Yasuhiro Kumai
      Pages 153-163
    4. Eiji Shimizu, Daisuke Matsuzawa
      Pages 165-170
  6. Midkine and the Urogenital System, Reproduction and Aging

    1. Front Matter
      Pages 171-171
    2. Waichi Sato, Kenji Kadomatsu
      Pages 173-182
    3. Masayasu Yamada, Yuuki Isaji, Shuntaro Ikeda
      Pages 183-193
    4. Yutaka Osuga, Yasushi Hirota, Kaori Koga, Osamu Yoshino, Tetsuya Hirata
      Pages 195-202
    5. Hisako Muramatsu, Peng Zou, Takashi Muramatsu
      Pages 203-210
    6. Astrid Liedert, Thorsten Schinke, Anita Ignatius, Michael Amling
      Pages 211-221
  7. Midkine and Cancer

    1. Front Matter
      Pages 223-223
    2. Yoshifumi Takei, Kenji Kadomatsu
      Pages 225-236
    3. Masatoshi Tagawa, Kiyoko Kawamura, Ling Yu, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada
      Pages 237-246
    4. Jerome Kerzerho, Florence Anne Castelli, Bernard Maillère
      Pages 247-258
    5. Zongbing You
      Pages 259-271
    6. Li Cheng Dai, Xing Yao, Jing Zhong
      Pages 273-282
    7. Özgür Kemik, Ahu Sarbay Kemik, A. Cumhur Dülger
      Pages 305-311
    8. Tadashi Kaname, Kumiko Yanagi, Hiroki Maehara
      Pages 313-319
  8. Back Matter
    Pages 321-336

About this book

Introduction

Carl Edward Sagan’s (1934-1996) one of the famous quatation was “Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than people.“ From past to date, well-known molecules, enzymes, proteins, lipids and carbonhydrates are studied in the pathogenesis of several diseases both as a diagnostic/prognostic biomarker and therapeutic agent. The underlying mechanism of unexplained diseases and failure of therapies are frequently studied with well-known biomarkers, but remain unclear in many cases. As Dr. Sagan said other keys are still waiting to be known in some forgetten corner of a body universe, we find strength to propose that one of them can be the growth factor with cytokine activity named “Midkine” This book summarizes the extensive up-to-date literature overeview with the lastest work of experts about midkine in a detailed format that conveys its role as both a pathologic factor and therapeutic agent.

Keywords

Development and reproduction Disease Midkine Survival and resistance Therapy

Editors and affiliations

  • Mine Ergüven
    • 1
  • Takashi Muramatsu
    • 2
  • Ayhan Bilir
    • 3
  1. 1.Faculty of Medicine, Faculty of BiochemistryYeni Yüzyıl UniversityIstanbulTurkey
  2. 2., Department of Health ScienceAichi Gakuin UniversityNisshinJapan
  3. 3., Department of Histology and EmbryologyIstanbul University Faculty of MedicineIstanbulTurkey

Bibliographic information

Industry Sectors
Pharma
Biotechnology
Consumer Packaged Goods