Bacillus thuringiensis Biotechnology

  • Estibaliz Sansinenea

Table of contents

  1. Front Matter
    Pages 1-1
  2. Bacillus thuringiensis: An Environmentally Safety Alternative

    1. Front Matter
      Pages 1-1
    2. Estibaliz Sansinenea
      Pages 3-18
    3. Zenas George, Neil Crickmore
      Pages 19-39
    4. Sarvjeet Kaur
      Pages 41-85
    5. Alvaro M. Florez, Cristina Osorio, Oscar Alzate
      Pages 93-113
  3. Genetics of Bacillus Thuringiensis

    1. Front Matter
      Pages 115-115
    2. Ole Andreas Økstad, Anne-Brit Kolstø
      Pages 117-129
    3. Gislayne T. Vilas-Bôas, Clelton A. Santos
      Pages 159-174
    4. Alejandra Ochoa-Zarzosa, Joel Edmundo López-Meza
      Pages 175-184
    5. Chengchen Xu, Yan Wang, Chan Yu, Lin Li, Minshun Li, Jin He et al.
      Pages 185-199
    6. Lobna Abdelkefi-Mesrati, Slim Tounsi
      Pages 201-214
  4. BT as Biopesticide: Applications in Biotechnology

    1. Front Matter
      Pages 229-229
    2. Anais S. Castagnola, Juan Luis Jurat-Fuentes
      Pages 283-304
    3. Bruce G. Hammond, Michael S. Koch
      Pages 305-325
  5. Other Bacillus Species in Biotechnology

    1. Front Matter
      Pages 327-327
    2. Noura Raddadi, Elena Crotti, Eleonora Rolli, Ramona Marasco, Fabio Fava, Daniele Daffonchio
      Pages 329-345
    3. Ines Chaabouni, Amel Guesmi, Ameur Cherif
      Pages 347-366
    4. J. E. Barboza-Corona, N. M. de la Fuente-Salcido, M. F. León-Galván
      Pages 367-384
  6. Back Matter
    Pages 373-373

About this book


Bacillus thuringiensis (Bt) has been used as a biopesticide in agriculture, forestry and mosquito control because of its advantages of specific toxicity against target insects, lack of polluting residues and safety to non-target organisms. The insecticidal properties of this bacterium are due to insecticidal proteins produced during sporulation. Despite these ecological benefits, the use of Bt biopesticides has lagged behind the synthetic chemicals. Genetic improvement of Bt natural strains, in particular Bt recombination, offers a promising means of improving efficacy and cost-effectiveness of Bt-based bioinsecticide products to develop new biotechnological applications. On the other hand, the different Bacillus species have important biotechnological applications; one of them is carried out by producing secondary metabolites, which are the study object of natural product chemistry. The amazing structural variability of these compounds has attracted the curiosity of chemists and the biological activities possessed by natural products have inspired the pharmaceutical industry to search for lead structures in microbial extracts. Screening of microbial extracts reveals the large structural diversity of natural compounds with broad biological activities, such as antimicrobial, antiviral, immunosuppressive, and antitumor activities that enable the bacterium to survive in its natural environment. These findings widen the target range of Bacillus spp., in special B. thuringiensis, besides insecticidal activity and help people to better understand its role in soil ecosystem.


Bacillus thuringiensis Biotechnology Environmental Management Genetic manipulation

Editors and affiliations

  • Estibaliz Sansinenea
    • 1
  1. 1.Autónoma de Puebla, Facultad de Ciencias QuímicasBenemérita UniversidadPueblaMexico

Bibliographic information

Industry Sectors
Materials & Steel
Chemical Manufacturing
Consumer Packaged Goods