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The Biology of Subcellular Nitric Oxide

  • Book
  • © 2012

Overview

  • Fills a gap in NO biology-related literature
  • Topics discussed have general biological relevance Interdisciplinary summary on recent advance on NO cellular biology
  • Chapter summaries and illustrations help rapid understanding of complex interactions
  • Can be used as a reference in scientific papers
  • Can be used as a lecture book
  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

  1. General Concepts

  2. Nitric Oxide Synthesis in Prokaryote Cells

  3. Nitric Oxide in Plant Organelles

  4. At the Edge of the Plant and Animal Kingdom

  5. Nitric Oxide Synthesis in Animal Cells

Keywords

About this book

This book fills in a gap in the NO literature. Recent progress in the field of NO-biology shows that NO is generated within distinct cell compartments, including specific plasma membrane regions, mitochondria, chloroplasts, peroxisomes, the Golgi-complex and intracellular membrane systems. NO synthesis plays specific roles in these compartments and, in turn, cell organelles also control intracellular NO levels. This monograph focuses on the roles played by the subcellular NO-signaling microdomains in the prokaryote-, fungus-, plant- and animal cells and shows how NO behaves as an intracellular signal in distinct cellular environments. This monograph also provides a summary of our knowledge on how NO synthesis came through evolution to be associated with organelles and subcellular compartments. Promotes the novel ideas that some functions of NO and its associations with subcellular units have been conserved during the evolution of the cell. A special chapter is dedicated to the biomedical relevance of subcellular NO synthesis, and this chapter also discusses the evidence that altered compartmentalization of NO-producing enzymes causes disease.

Authors and Affiliations

  • Cardiovascular Research Center, Spanish National, Madrid, Spain

    Tamás Rőszer

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