Stem Cells and Cancer Stem Cells,Volume 3

Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 3

  • M.A. Hayat

Part of the Stem Cells and Cancer Stem Cells book series (STEM, volume 3)

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. General Introduction

    1. Front Matter
      Pages 1-1
    2. M.A. Hayat
      Pages 3-5
    3. Seong-Wook Yun, Nam-Young Kang, Young-Tae Chang
      Pages 7-14
    4. Katsuhiro Kita, Gerd G. Gauglitz, Stephen Williamson, David N. Herndon, Thang T. Phan, Marc G. Jeschke
      Pages 15-21
    5. Mario Ricciardi, Luciano Pacelli, Giulio Bassi, Francesco Bifari, Federico Mosna, Mauro Krampera
      Pages 23-33
    6. Emilie Legué, Inês Sequeira, Jean-François Nicolas
      Pages 35-47
    7. Krzysztof M. Mrozik, Jimin Xiong, Peter S. Zilm, Stan Gronthos, P. Mark Bartold
      Pages 75-94
  3. Molecular Genetics

  4. Therapy

    1. Front Matter
      Pages 155-155
    2. Juan Antonio Marchal, María Angel García, Houria Boulaiz, Macarena Perán, Pablo Álvarez, José Carlos Prados et al.
      Pages 157-171
    3. Alejandra Negro, Cynthia St. Hilaire, Manfred Boehm
      Pages 173-178

About this book


It is pointed out that cancer stem cell is a cell type within a tumor that possesses the capacity of cell-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. It is emphasized that a cancer stem cell is a tumor initiating cell. That conventional chemotherapy kills most cells in a tumor, but cancer stem cells remain intact is discussed. Vast applications of stem cells, cancer stem cells, mesenchymal stem cells, and human pluripotent stem cells are discussed. Because human embryonic stem cells possess the potential of producing unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume. Because of the pluripotency of embryonic stem cells, this volume discusses various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological uses. The role of these cells in cell differentiation is also included. The role of cancer stem cells of breast, colon, and melanoma tumors in response to antitumor therapy is detailed. The role of cancer stem cells, specifically in the deadliest brain cancer, glioblastoma multiforme, is explained. Transplantation of bone marrow-derived stem cells for myocardial infarcation and use of mesenchymal stem cells in orthopedics are described.


1. Stem cells 2. Cancer stem cells 3. Tissue engineering 4. Regenerative medicine 5. Tumor development

Editors and affiliations

  • M.A. Hayat
    • 1
  1. 1., Kean UniversityRoom 213, Library buildingUnionUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 2012
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-2414-3
  • Online ISBN 978-94-007-2415-0
  • About this book
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