Advertisement

Antibody Expression and Production

  • Mohamed Al-Rubeai

Part of the Cell Engineering book series (CEEN, volume 7)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Thomas Jostock
    Pages 1-24
  3. Darrin Kuystermans, Mohamed Al-Rubeai
    Pages 25-52
  4. Hideki Yamaji
    Pages 53-76
  5. Dongxing Zha, Thomas Linden, Thomas Potgieter
    Pages 77-98
  6. Georg Melmer, Stephan Hellwig, Grit Hehmann, Ulrike Dahlems
    Pages 99-119
  7. Yoshinori Kawabe, Masamichi Kamihira
    Pages 121-141
  8. Alejandro Sarrion-Perdigones, Paloma Juarez, Antonio Granell, Diego Orzaez
    Pages 143-164
  9. Hiroshi Tachibana, Masataka Takekoshi
    Pages 165-178
  10. Silvia Biocca
    Pages 179-195
  11. Lisa E. Goldsmith, Matthew K. Robinson
    Pages 197-233
  12. Dafne Müller, Roland E. Kontermann
    Pages 235-249
  13. Maureen Spearman, Ben Dionne, Michael Butler
    Pages 251-292
  14. XueJun Han, Arthur Hewig, Ganesh Vedantham
    Pages 305-340
  15. Back Matter
    Pages 341-345

About this book

Introduction

Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, production and applications of antibody. It provides the necessary theoretical background and description of methods for the expression of antibody in microbial and animal cell cultures and in transgenic animals and plants. There is a strong focus on those issues related to the production of intrabodies, bispecific antibody and antibody fragments and also to novel applications in cancer immunotherapy.

Keywords

Antibody Biopharmaceuticals Cell Culture Production and Development Therapeutic and diagnostic antibody

Editors and affiliations

  • Mohamed Al-Rubeai
    • 1
  1. 1.Dept. Chemical & Biochemical, EngineeringUniversity College, DublinBelfield, Dublin 4Ireland

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-1257-7
  • Copyright Information Springer Science+Business Media B.V. 2011
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-1256-0
  • Online ISBN 978-94-007-1257-7
  • Series Print ISSN 1389-6946
  • Buy this book on publisher's site
Industry Sectors
Pharma
Biotechnology
Consumer Packaged Goods