From Molecular to Modular Tumor Therapy

Tumors are Reconstructible Communicatively Evolving Systems

  • Albrecht Reichle

Part of the The Tumor Microenvironment book series (TTME, volume 3)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Therapy-Derived Systems Biology: A Pragmatic Communication Theory

  3. Tumors Share Common Processes During Tumor Evolution: Communicative Aspects of a Situation’s Interpretation for Creating Systems-Directed Therapies

  4. Systems-Relevant Molecular and Cellular Targets: Implementation of Modular ‘Knowledge’

    1. Front Matter
      Pages 159-159
    2. Ilse M. E. Beck, Guy Haegeman, Karolien De Bosscher
      Pages 191-242
  5. Tumors are Evolvable Modular and Rationalized Systems: From Molecular to Modular Tumor Therapy

    1. Front Matter
      Pages 263-263
    2. Albrecht Reichle, Thomas Vogt
      Pages 265-285
    3. Albrecht Reichle, Gerhard C. Hildebrand
      Pages 305-309
  6. Biomodulatory Therapy Approaches in Metastatic Cancer

    1. Front Matter
      Pages 311-311

About this book

Introduction

The traditional problem of the poor presentability as well as diagnostic and therapeutic practicability of individual patient care is still unresolved. The present book aims at leading the reader (cancer researchers, pharmacologists, biologists) away―in a scientifically accessible manner―from the daily conflicts between theory and practice and between the generalized and individual tumor patient, so that more personalized diagnostic and therapeutic strategies can be developed for controlling metastatic tumor disease: • First, recording the systems concept of tumor biology based on rather different sciences (biochemistry, cell biology, and medical oncology) including their potential contribution to communication, • then, giving reductionistically derived systems features an internal communicative context (formal-pragmatic communication theory), and • finally, binding the systems features to (tumor-immanent) evolutionary processes (modularity of biochemical and cellular processes, rationalization of biologic functions).

Keywords

Carcinom Communication theory (integration of communication) Evolution, modularity Holism-reductionism Tumor models Tumor-associated inflammation regulation

Editors and affiliations

  • Albrecht Reichle
    • 1
  1. 1., Department of Hematology and OncologyUniversity Hospital RegensburgRegensburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-90-481-9531-2
  • Copyright Information Springer Science+Business Media B.V. 2010
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-90-481-9530-5
  • Online ISBN 978-90-481-9531-2
  • About this book
Industry Sectors
Biotechnology
Pharma