Adhesion of Cells, Viruses and Nanoparticles

  • Kevin Kendall
  • Michaela Kendall
  • Florian Rehfeldt

Table of contents

  1. Front Matter
    Pages i-xv
  2. Fundamentals

    1. Front Matter
      Pages 1-1
    2. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 3-20
    3. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 21-43
    4. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 45-71
  3. Mechanisms

    1. Front Matter
      Pages 73-73
    2. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 75-99
    3. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 101-121
    4. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 123-143
    5. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 145-165
  4. Detailed Research

    1. Front Matter
      Pages 167-167
    2. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 169-193
    3. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 195-220
    4. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 221-240
    5. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 241-264
    6. Kevin Kendall, Michaela Kendall, Florian Rehfeldt
      Pages 265-275
  5. Back Matter
    Pages 277-282

About this book

Introduction

"Adhesion of Cells, Viruses and Nanoparticles" describes the adhesion of cells, viruses and nanoparticles starting from the basic principles of adhesion science, familiar to postgraduates, and leading on to recent research results.

The underlying theory is that of van der Waals forces acting between cells and substrates, embodied in the molecules lying at the surfaces, together with the geometry and elasticity of the materials involved.

The first part describes the fundamental background to adhesion principles, including the phenomenology, the important equations and the modeling ideas. Then the mechanisms of adhesion are explored in the second part, including the elastic deformations of spheres and the importance of the energy of adhesion as measured in various tests. It is demonstrated that adhesion of cells is statistical and depends on Brownian movement and on the complex multiple contacts that can form as cells move around. Then, detailed chapters on cell adhesion, contact of viruses and aggregation of nanoparticles follow in Part 3. Finally, the last chapter looks to the future understanding of cell adhesion and points out some interesting directions of research, development and treatment of diseases related to these phenomena.

This book is an ideal resource for researchers on adhesion molecules, receptors, cell and tissue culturing, virus infection, toxicity of nanoparticles and bioreactor fouling. It can also be used to support undergraduate and Masters level teaching courses.

"This is a fascinating book and it is an invaluable resource for understanding particle-particle/surface adhesion at micro- and nano- scales. I intend to keep one for my future reference and highly recommend it to my students."

(Prof. Zhibing Zhang, School of Chemical Engineering, University of Birmingham, UK)

Keywords

Biological Adhesives Cell Adhesion Elastic deformation Geometrical Variation Molecular attraction Plant Cells

Authors and affiliations

  • Kevin Kendall
    • 1
  • Michaela Kendall
    • 2
  • Florian Rehfeldt
    • 3
  1. 1.School of Engineering, Dept. Chemical EngineeringUniversity of BirminghamBirminghamUnited Kingdom
  2. 2.European Centre for Environment and Huma, Peninsula College of Medicine and DentisExeter UniversityTruroUnited Kingdom
  3. 3., 3rd Institute of Physics - BiophysicsGeorg-August-Universität GöttingenGöttingenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-90-481-2585-2
  • Copyright Information Springer Science+Business Media B.V. 2011
  • Publisher Name Springer, Dordrecht
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-90-481-2584-5
  • Online ISBN 978-90-481-2585-2
  • About this book
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