Free Radicals in Human Health and Disease

  • Vibha Rani
  • Umesh Chand Singh Yadav

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Free Radical Generation

    1. Front Matter
      Pages 1-1
    2. Susinjan Bhattacharya
      Pages 17-29
    3. Sudha Srivastava, Kushagr Punyani, Shuchi Arora
      Pages 31-41
    4. Vibha Rani, Suryma Asthana, Mohit Vadhera, Umesh Chand Singh Yadav, Neha Atale
      Pages 43-56
  3. Mechanism of Oxidative Stress

    1. Front Matter
      Pages 57-57
    2. M. M. Towhidul Islam, Hossain Uddin Shekhar
      Pages 59-73
    3. Shanthi Sri Vundru, Nupoor Prasad, Rohit Patel, Vibha Rani, Umesh Chand Singh Yadav
      Pages 75-90
    4. Neeraj Dholia, Prerna Ramteke, Johnna F. Varghese, Vibha Rani, Umesh Chand Singh Yadav
      Pages 91-103
    5. Vibha Rani, Shivangi Mishra, Tanuja Yadav, Umesh Chand Singh Yadav, Shrey Kohli
      Pages 105-116
  4. Oxidative Stress and Diseases

    1. Front Matter
      Pages 117-117
    2. Navrattan Kaur, Bibekananda Sarkar, Sunil Mittal, Monisha Dhiman, Gulio Taglialatela, Regino J. Perez-Polo et al.
      Pages 175-207
    3. Vibha Rani, Khushboo Gupta
      Pages 209-225
    4. Reena Negi, Deepti Pande, Kanchan Karki, Ashok Kumar, Ranjana S. Khanna, Hari D. Khanna
      Pages 227-239
    5. Rachana, Shruti Thakur, Sujata Basu
      Pages 241-257
    6. Monisha Dhiman, Shweta Thakur, Shishir Upadhyay, Amandeep Kaur, Anil K. Mantha
      Pages 259-278
    7. Kanti Bhooshan Pandey, Syed Ibrahim Rizvi
      Pages 279-290
  5. Strategies to Ameliorate Oxidative Stress Induced Diseases

    1. Front Matter
      Pages 291-291
    2. Saikat Sen, Raja Chakraborty
      Pages 293-322
    3. Kanchan Karki, Deepti Pande, Reena Negi, Seema Khanna, Ranjana S. Khanna, Hari D. Khanna
      Pages 323-334
    4. Rahul Checker, Deepak Sharma, Santosh K. Sandur
      Pages 335-349
    5. Deepti Pande, Reena Negi, Kanchan Karki, Seema Khanna, U. S. Dwivedi, Ranjana S. Khanna et al.
      Pages 351-368
    6. Reema Gabrani, Garima Sharma, Shweta Dang, Sanjay Gupta
      Pages 369-379
    7. Shweta Dang, Sonal Gupta, Rakhi Bansal, Javed Ali, Reema Gabrani
      Pages 397-415
    8. Dominic Agyei, Michael K. Danquah, Indira P. Sarethy, Sharadwata Pan
      Pages 417-430

About this book


The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society.

The present book is aimed at graduate students, researchers in academia, industry, and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.


Antioxidants Cell Death Inflammation Pathophysiology

Editors and affiliations

  • Vibha Rani
    • 1
  • Umesh Chand Singh Yadav
    • 2
  1. 1.Department of BiotechnologyJaypee Institute of Information TechnologyNoidaIndia
  2. 2.School of Life SciencesCentral University of GujaratGandhinagarIndia

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