Cardiac-Vascular Remodeling and Functional Interaction

1. Front Matter

   Pages I-XII

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2. Introduction

   1. Introduction

      • Joseph S. Janicki, Masatsugu Hori, Yukio Maruyama

      Pages 1-2

3. Ventricular—Vascular Adaptation and Remodeling

   1. Front Matter

      Pages 3-3

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   2. Vascular Remodeling During Heart Failure

      • Sylvia Heeneman, Jos F. M. Smits, Mat J. A. P. Daemen

      Pages 5-18

   3. Myocardial Interstitial Collagen Matrix Remodeling in Response to a Chronic Elevation in Ventricular Preload or Afterload

      • Joseph S. Janicki, Scott E. Campbell, Jeffrey R. Henegar, Gregory L. Brower

      Pages 19-31

   4. Myocardial Hypertrophy and Coronary Circulation Before and After Relief of Pressure Overload

      • Shogen Isoyama

      Pages 33-46

   5. Cardiac Hypertrophy and the Renin-Angiotensin System

      • Louis J. Dell’Italia

      Pages 47-66

   6. The Role of Manganese Superoxide Dismutase in the Acquisition of Tolerance of the Heart to Ischemia: Molecular Adaptation to Ischemia

      • Masashi Nishida, Tsunehiko Kuzuya, Shiro Hoshida, Nobushige Yamashita, Masatsugu Hori, Michihiko Tada

      Pages 67-77

   7. Remodeling: How Vessels Narrow

      • Stephen M. Schwartz

      Pages 79-90

4. Systolic—Diastolic Interaction

   1. Front Matter

      Pages 91-91

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   2. Interaction Between Left-Ventricular Function and Loading Condition in Cardiovascular Disease

      • Yukio Maruyama, Kazuhira Maehara, Tomiyoshi Saito, Shuichi Saitoh, Masahiko Sato, Minoru Mitsugi

      Pages 93-104

   3. Intraventricular Interaction

      • Yoichi Goto

      Pages 105-113

   4. Adaptation of the Cardiac Cell to Loading: Function in Heart Failure

      • Henk E. D. J. ter Keurs

      Pages 115-132

   5. Transient Hemodynamic Perturbations: An Approach to the Study of Ventricular Interaction and Restoring Forces

      • Martin M. LeWinter

      Pages 133-141

   6. Extrinsic Versus Intrinsic Determinants of the Diastolic Pressure—Volume Relation

      • David A. Kass

      Pages 143-162

   7. Endocardial—Myocardial Interaction

      • Gilles W. De Keulenaer, Luc J. Andries, Paul F. Fransen, Puneet Mohan, Gregory Kaluza, Jean L. Rouleau et al.

      Pages 163-178

5. Ventricular—Vascular Interaction

   1. Front Matter

      Pages 179-179

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   2. Arterial Compliance as Load on the Heart

      • Nico Westerhof, Nikos Stergiopulos, O. S. Randall, Gerard C. van den Bos

      Pages 181-188

   3. Optimal Afterload that Maximizes External Work and Optimal Heart that Minimizes O2 Consumption

      • Masaru Sugimachi, Kenji Sunagawa

      Pages 189-202

   4. Influence of Aortic Impedance on the Development of Pressure-Overloaded Left-Ventricular Hypertrophy in Rats

      • Masunori Matsuzaki, Shigeki Kobayashi, Michihiro Kohno, Masafumi Yano, Tsutomu Ryoke, Tomoko Ohkusa et al.

      Pages 203-216

Cardiac performance is regulated not only by cardiac muscle properties but also by several other factors, including those associated with the neurohumoral system and the mechanical characteristics of the peripheral circulation. New information con­ cerning these regulatory factors has furthered our understanding of the pathophysi­ ology of cardiac dysfunction. However, controversy remains, along with a need to integrate these multidisciplinary findings. It was with this in mind, together with my continuing interest in the response of the normal and diseased heart to variations in loading conditions, that the satellite symposium entitled "Interactions Between Car­ diac Function and Vascular Dynamics" was organized and dedicated to my mentor, Dr. T. Takishima. The symposium was held in Fukushima, Japan, in 1992 following the Tenth Inter­ national Conference of the Cardiovascular Systems Dynamics Society in Kobe, Japan, which was organized by the then president of the society, Dr. Masatsugu Hori. The Fukushima symposium and the Kobe conference were stimulating and informative. To commemorate these events, Dr. Hori, Dr. Janicki, and I decided to publish this book. It covers topics that were presented then as well as pertinent new material. As a result, the book includes not only updated reviews but also up-to-date findings that were not considered at the two scientific sessions. The high level attained in this book is due to the outstanding contributions from internationally renowned scientists. This final product of their efforts should prove to be a valuable source of information to the reader.

• adaptation
• artery
• cardiac function
• cardiovascular
• circulation
• endothelium
• heart
• heart disease
• heart failure
• nitric oxide
• research
• vascular disease

• First Department of Internal Medicine, Fukushima Medical College, Fukushima, Japan

  Yukio Maruyama

• First Department of Medicine, Osaka University School of Medicine, Suita, Osaka, 565, Japan

  Masatsugu Hori

• College of Veterinary Medicine, Auburn University, Auburn, USA

  Joseph S. Janicki

Policies and ethics