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Marginal Donors

Current and Future Status

  • Book
  • © 2014

Overview

  • First book focusing on marginal donors

  • Covers multiple organs

  • Offers a comprehensive overview of organ transplantation, from basic research to the latest clinical experience

  • Includes supplementary material: sn.pub/extras

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Table of contents (24 chapters)

  1. Kidney Transplantation

  2. Pancreas Transplantation

  3. Islet Transplantation

  4. Small Intestine Transplantation

  5. ABO-Incompatible Donor

Keywords

About this book

In response to persistent donor organ shortages, organs from marginal donors, such as expanded criteria donors (ECD) and donation after cardiac death (DCD) donors, are now accepted and have been successfully transplanted, reducing the waiting times for transplantation. Especially in Japan, transplantation of DCD kidneys has a relatively long history because of the difficulty or lack of national consensus in accepting brain death, which has made it possible to accumulate considerable clinical experience. Thus, the current organ shortage has stimulated interest in the use of marginal donors for transplantation. On the other hand, however, it is known that these organs have a high rate of delayed graft function and a more complicated postoperative course. These drawbacks have created the greatest clinical challenge in transplantation to date because of the current shortage and limitations of donors using ECD and DCD.

This book, prepared by distinguished authorities in their fields, is intended for clinicians and researchers. It highlights the use of marginal donors as a comparatively novel source of transplantation organs and provides a thorough overview of marginal donors from their historical origins to recent clinical applications, including the state-of-the-art science of organ/donor management, procurement, and preservation. Also provided is valuable information on ABO-incompatible donors which extend the availability of donor sources. Each chapter offers an individual analysis of the optimal requirements for the safe management and preservation of organs, including the heart, lung, liver, kidney, pancreas, and pancreatic islets.

Reviews

From the reviews:

“The book clearly and thoroughly outlines the international history and experience by organ and criteria. It also includes the key components of implementation, including pertinent ethical considerations and key technical considerations. … this book is appropriate for medical and surgical transplant practitioners and organ procurement administrative specialists. … The book nicely catalogues and summarizes experience that is largely represented in the current literature and debate. … This is a complete and well-written book about a timely subject.” (Jeffrey Lowell, Doody’s Book Reviews, June, 2014)

Editors and Affiliations

  • Department of Surgery and Clinical Research Center, Chiba-East National Hospital,, Chiba, Japan

    Takehide Asano

  • Department of Therapeutics for End-Stage Organ Dysfunction, Osaka University Graduate School of Medicine, Suita, Japan

    Norihide Fukushima

  • Department of Organ Transplant Surgery, Fujita Health University, Aichi, Japan

    Takashi Kenmochi

  • Division for Innovative Surgery and Transplantation, National Center for Child Health and Development, Setagaya-ku, Japan

    Naoto Matsuno

Bibliographic Information

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