Angiogenesis in Inflammation: Mechanisms and Clinical Correlates

  • Michael P. Seed
  • David A. Walsh

Part of the Progress in Inflammation Research book series (PIR)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Paul L. Mapp, David A. Walsh
    Pages 1-13
  3. Elena Riboldi, Silvano Sozzani, Marco Presta
    Pages 29-43
  4. Ewa Paleolog, Mohammed Ali Akhavani
    Pages 45-57
  5. Patrick Auguste, François Vincent, Giulio Gabbiani, Alexis Desmoulière
    Pages 59-82
  6. Zoltán Szekanecz, Alisa E. Koch
    Pages 83-98
  7. Chandan Alam, Paul Colville-Nash, Michael Seed
    Pages 99-148
  8. David A. Walsh, Eirlys Williams
    Pages 149-175
  9. Back Matter
    Pages 177-182

About this book

Introduction

Angiogenesis is an essential component of inflammation and its resolution. This volume provides up-to-date information on the latest developments in the pathology, mechanisms and therapy of angiogenesis dependent inflammatory disease. Recent years have seen large advances in angiogenesis research, especially in oncology. Traditionally mechanisms in inflammation angiogenesis were inferred from tumour angiogenesis, however recent research has matured highlighting the similarities and dissimilarities between these processes. This volume relates the lessons learned from tumour biology applied to inflammation.

This issue of Angiogenesis in Inflammation: Mechanisms and Clinical Correlates develops current knowledge on the mechanisms at the molecular and cellular levels as they relate to inflammation, including acute and chronic inflammation, neurogenic initiation, and the role of the multiple cellular components that comprise inflammation: granulocytes, macrophages, fibroblasts, dendritic cells and lymphocytes. This is related to inflammatory disease: not only the familiar angiogenesis dependent diseases of rheumatoid arthritis and psoriasis, but also loci such as the lung, gastric ulcers, the eye with uveitis, wound healing and periodontal disease and their therapy, how this knowledge may be used in the discovery of novel therapeutics. The volume brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and disease, culminating in a discourse on areas for future therapies.

Keywords

Chemokine Macrophages angiogenesis biology cell cellular processes cytokine cytokines development diseases inflammation lymphocytes pathology psoriasis tumor

Editors and affiliations

  • Michael P. Seed
    • 1
  • David A. Walsh
    • 2
  1. 1.Centre for Experimental Medicine and Rheumatology William Harvey Research InstituteSt. Bartholomew’s HospitalLondonUK
  2. 2.Academic RheumatologyUniversity of NottinghamNottinghamUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7643-7650-5
  • Copyright Information Birkhäuser Basel 2008
  • Publisher Name Birkhäuser Basel
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7643-7626-0
  • Online ISBN 978-3-7643-7650-5
  • About this book
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