Overview
- Most recent and comprehensive book about Leishmania and Leishmaniasis
- A useful and copious guide for clinicians and researchers alike, working in the area of infectious disease and vaccine development.
- Describes epidemiology, pathology and molecular features of Leishmaniasis and drug resistance
- Edited and written by experts in the field. Discusses ideas for novel therapies
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Table of contents (20 chapters)
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Front Matter
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Determinant Features in Leishmaniasis
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Front Matter
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DETERMINANT FEATURES IN LEISHMANIASIS
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Leishmania and the Immune System
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Front Matter
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LEISHMANIA AND THE IMMUNE SYSTEM
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Challenges in the Diagnosis, Treatment and Control of Leishmaniasis in Times of Drug Resistance
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Front Matter
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CHALLENGES IN THE DIAGNOSIS, TREATMENT AND CONTROL OF LEISHMANIASIS IN TIMES OF DRUG RESISTANCE
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Molecular Features of Drug-Resistant Leishmania
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Front Matter
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MOLECULAR FEATURES OF DRUG-RESISTANT LEISHMANIA
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Pharmacology and Chemotherapy of Leishmaniasis
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Front Matter
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Keywords
About this book
Editors and Affiliations
About the editors
Professor Dr. Emilia Diaz
Emilia Diaz studied Pharmacy at the Central University of Venezuela (UCV) in Caracas and became Doctor of Sciences in Pharmacology in 2003 in the same university. From 1999 to 2003 she was Assistant Professor at the Chair of Biology, Faculty of Pharmacy, UCV. Currently she is Aggregate Professor of Human Physiology, Faculty of Medicine, UCV. Initially her research interests were related to the comprehension of the mechanisms involved in the diuretic and natriuretic action of adrenomedullin, and the role of the dopaminergic system in the adrenomedullin-induced diuresis and natriuresis. Recently her research interests are focused towards the comprehension of the mechanisms involved in proficiency and fitness in drug resistant Leishmania and in the initial interaction events (chemotaxis) occurring between Leishmania and its host cell.
Professor Dr. Maritza Padrón Nieves
Maritza Padrón Nieves studied Biology at UCV in Caracas and became Magister Scientiarum in Pharmacology in 1993 and Doctor of Sciences in Pharmacology in 2011 in the same university. From 1994 to 2000 she was head of the Department of Basic Sciences at the School of Nursery, UCV. Currently she is Aggregate Professor and head of the Human Pharmacology and Toxicology Chair, Faculty of Medicine, UCV. Initially her research interests were related to the comprehension of the mechanisms involved in digoxin intoxication. Recently she has dedicated her scientific interest to the identification and characterization of molecular markers of resistance in the Leishmania sp. infection model.
Professor Dr. Alicia Ponte-Sucre
Alicia Ponte-Sucre studied Education in Biological Sciences at the Andrés Bello Catholic University in Caracas and became Magister Scientiarum in Physiology and Biophysics in 1981 at the Venezuelan Institute ofScientific Research and Doctor of Sciences in Pharmacology in 1993 at the UCV. She spent a year (1999-2000) at the University of Würzburg with a scholarship from the Alexander von Humboldt Foundation and was a staff scientist (2003-2007) at the same university, within a multidisciplinary project from the German Research Council. Currently she is Full Professor in Human Physiology and Coordinator for Scientific Affairs of the Faculty of Medicine, UCV. Initially, her studies were focused on the physical-chemical behavior of black lipid membranes. Later, her scientific activity was oriented towards the characterization of receptors involved in air-way smooth muscle contraction. Recently her interests have been focused towards the study of parasite metabolism and membrane transporters essential for parasite survival and involved in drug resistance, and the mechanisms involved in cellular differentiation and parasite-host interaction in the Leishmania model. Additionally she has characterized natural products and target oriented designed compounds as potential therapeutic agents.
Bibliographic Information
Book Title: Drug Resistance in Leishmania Parasites
Book Subtitle: Consequences, Molecular Mechanisms and Possible Treatments
Editors: Alicia Ponte-Sucre, Emilia Diaz, Maritza Padrón-Nieves
DOI: https://doi.org/10.1007/978-3-7091-1125-3
Publisher: Springer Vienna
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag Wien 2013
Hardcover ISBN: 978-3-7091-0238-1Published: 04 September 2012
eBook ISBN: 978-3-7091-1125-3Published: 04 September 2012
Edition Number: 1
Number of Pages: XIV, 462
Topics: Infectious Diseases, Drug Resistance, Pharmaceutical Sciences/Technology, Vaccine, Parasitology, Microbiology
Industry Sectors: Biotechnology, Health & Hospitals, Pharma