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Metal Ions in Neurological Systems

  • Wolfgang Linert
  • Henryk Kozlowski

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Robert R. Crichton, David T. Dexter, Roberta J. Ward
    Pages 1-15
  3. Elizabeth Milward, Bulent Acikyol, Brianna Bassett, Evan Williams, Ross Graham, Roheeth Delima et al.
    Pages 17-29
  4. Eleni Siakkou, Guy N. L. Jameson
    Pages 41-46
  5. Guido Crisponi, Valeria Marina Nurchi, Clara Gerosa, Daniela Fanni, Sonia Nemolato, Gavino Faa
    Pages 47-63
  6. Yuzo Nishida
    Pages 65-76
  7. Alberto Granzotto, Silvia Bolognin, Janez Scancar, Radmila Milacic, Paolo Zatta
    Pages 85-94
  8. Christopher Exley, Emily R. House
    Pages 95-101
  9. Valeria Marina Nurchi, Guido Crisponi, Valerio Bertolasi, Gavino Faa, Maurizio Remelli
    Pages 103-123
  10. Csilla Kállay, Ildikó Turi, Sarolta Timári, Zoltán Nagy, Daniele Sanna, Giuseppe Pappalardo et al.
    Pages 189-197
  11. Éva Sija, Annalisa Dean, Tamás Jakusch, Valerio B. Di Marco, Alfonso Venzo, Tamás Kiss
    Pages 199-210
  12. Sylvain Bohic, Dominic Hare, Alexia Daoust, Peter Cloetens, Emmanuel L. Barbier
    Pages 211-222
  13. Yonghwang Ha, Olga G. Tsay, David G. Churchill
    Pages 223-238
  14. Back Matter
    Pages 239-243

About this book

Introduction

Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic.

Keywords

metal ions metalloproteins neurological systems

Editors and affiliations

  • Wolfgang Linert
    • 1
  • Henryk Kozlowski
    • 2
  1. 1., Institute of Applied Synthetic ChemistryVienna University of TechnologyViennaAustria
  2. 2.Faculty of ChemistryUniversity of WroclawWroclawPoland

Bibliographic information

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Biotechnology