Store-operated Ca2+ entry (SOCE) pathways

Emerging signaling concepts in human (patho)physiology

  • Klaus Groschner
  • Wolfgang F. Graier
  • Christoph Romanin

Table of contents

  1. Front Matter
    Pages i-xxi
  2. SOCE: Fundamental Mechanistic Concepts

    1. Front Matter
      Pages 1-1
    2. James W. Putney
      Pages 3-13
    3. Peter B. Stathopulos, Mitsuhiko Ikura
      Pages 15-31
    4. Patrick G. Hogan
      Pages 33-44
    5. Rainer Schindl, Marc Fahrner, Martin Muik, Christoph Romanin
      Pages 45-56
    6. Jeong Hee Hong, Min Seuk Kim, Kyu Pil Lee, Joseph P. Yuan, Shmuel Muallem
      Pages 57-72
    7. Indu S. Ambudkar, Kwong Tai Cheng, Hwei Ling Ong, Xibao Liu
      Pages 73-92
    8. Claudia Moreno, Luis Vaca
      Pages 93-113
  3. SOCE: Crosstalk Between Organelle and Cellular Compartments

    1. Front Matter
      Pages 131-131
    2. Anant B. Parekh
      Pages 133-135
    3. Hayley Dingsdale, Lee Haynes, Gyorgy Lur, Alexei Tepikin
      Pages 137-151
    4. Javier García-Sancho, María Teresa Alonso
      Pages 153-162
    5. Alexis Bavencoffe, Michael Xi Zhu
      Pages 163-175
    6. András Spät, Gergö Szanda
      Pages 177-192
    7. Nicolas Demaurex, Maud Frieden
      Pages 193-209
    8. Roland Malli, Wolfgang F. Graier
      Pages 211-229
    9. Nicola Fameli, A. Mark Evans, Cornelis van Breemen
      Pages 231-247
    10. Lothar A. Blatter
      Pages 249-263

About this book


Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.


Calcium Entry Calcium Signaling ORAI Pathway STIM Pathway Transient Receptor Potential TRP

Editors and affiliations

  • Klaus Groschner
    • 1
  • Wolfgang F. Graier
    • 2
  • Christoph Romanin
    • 3
  1. 1.Center for Physiological MedicineMedical University of GrazGrazAustria
  2. 2., Center for Molecular MedicineMedical University of GrazGrazAustria
  3. 3., Institute of BiophysicsUniversity of LinzLinzAustria

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag/Wien 2012
  • Publisher Name Springer, Vienna
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7091-0961-8
  • Online ISBN 978-3-7091-0962-5
  • About this book
Industry Sectors
Consumer Packaged Goods