Metabolism of Human Diseases

Organ Physiology and Pathophysiology

  • Eckhard Lammert
  • Martin Zeeb

Table of contents

  1. Front Matter
    Pages i-ix
  2. Martin Zeeb, Eckhard Lammert
    Pages 1-2
  3. Brain

    1. Front Matter
      Pages 3-3
    2. Lorraine V. Kalia
      Pages 5-10
    3. Donatella Marazziti, Grazia Rutigliano, Stefano Baroni, Liliana Dell’Osso
      Pages 11-16
    4. Peter F. Buckley, Adriana Foster
      Pages 17-22
    5. Wesley Plinke, Detlev Boison
      Pages 23-27
    6. Giulia Ambrosi, Silvia Cerri, Fabio Blandini
      Pages 29-33
    7. Milos D. Ikonomovic, Steven T. DeKosky
      Pages 35-40
    8. Massimo Leone, Paola Di Fiore
      Pages 41-45
    9. Markus Kipp
      Pages 47-52
    10. Maria D. Torres, Jorge Busciglio
      Pages 53-56
  4. Eye

    1. Front Matter
      Pages 57-57
    2. Anja Mataruga, Frank Müller
      Pages 59-65
    3. Monika Fleckenstein, Frank G. Holz
      Pages 67-72
    4. Samuel D. Crish, Christine M. Dengler-Crish
      Pages 73-77
  5. Teeth and Bones

    1. Front Matter
      Pages 79-79
    2. Kazuhiko Kawasaki, Kenneth M. Weiss
      Pages 81-85
    3. Colin Robinson
      Pages 87-92
    4. Emmanuel Biver, René Rizzoli
      Pages 93-98

About this book


Metabolism of Human Diseases” examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The latter include depression, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, migraine, multiple sclerosis, Down syndrome, macular degeneration, glaucoma, asthma, COPD, pneumonia, atherosclerotic heart disease, heart failure, stroke, varicose veins, Sickle cell disease, hyperlipidemia, fever, sepsis, allergies, peptic ulcer, gastroenteritis, lactose intolerance, colon cancer, diabetes, cirrhosis, metabolic syndrome, hypertension, chronic kidney disease, gout, urinary tract infections, kidney stones, dental caries, osteoporosis, osteoarthritis, rheumatoid arthritis, breast cancer and prostate cancer. The book also describes commonly used drugs and explains their molecular targets. It provides the first comprehensive and detailed summary of the metabolism of individual organs and their physiological and pathological functioning. Thus it serves as a useful supplement to previous textbooks of human physiology. “Metabolism of Human Diseases is a must-have, state-of-the-art textbook written by International experts for graduate students, postdocs and scientists in metabolic research, biochemistry, physiology and pharmacy as well as for physicians interested in molecular mechanisms underlying common human diseases.



biochemical metabolism drug treatment key organs lipid metabolism metabolic diseases pathological metabolic changes physiological consequences physiological functioning

Editors and affiliations

  • Eckhard Lammert
    • 1
  • Martin Zeeb
    • 2
  1. 1.Institute of Metabolic Physiology, German Diabetes CenterHeinrich Heine University DüsseldorfDüsseldorfGermany
  2. 2.CardioMetabolic Diseases ResearchBoehringer Ingelheim Pharma GmbH & Co KGBiberachGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Wien 2014
  • Publisher Name Springer, Vienna
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7091-0714-0
  • Online ISBN 978-3-7091-0715-7
  • About this book
Industry Sectors
Consumer Packaged Goods