Field-Flow Fractionation in Biopolymer Analysis

  • S. Kim R. Williams
  • Karin D. Caldwell

Table of contents

  1. Front Matter
    Pages i-x
  2. Karl-Gustav Wahlund, Lars Nilsson
    Pages 1-21
  3. Galina E. Kassalainen, S. Kim Ratanathanawongs Williams
    Pages 23-36
  4. Pierluigi Reschiglian, Andrea Zattoni, Barbara Roda, Diana C. Rambaldi, Myeong Hee Moon
    Pages 37-55
  5. Myeong Hee Moon, Ki Hun Kim, Dukjin Kang
    Pages 57-71
  6. Joey Pollastrini, Linda O. Narhi, Yijia Jiang, Shawn Cao
    Pages 73-88
  7. Jun Liu, Qing Zhu, Steven J. Shire, Barthélemy Demeule
    Pages 89-101
  8. Robert Y. -T. Chou, Joey Pollastrini, Thomas M. Dillon, Pavel V. Bondarenko, Lei-Ting T. Tam, Jill Miller et al.
    Pages 113-126
  9. Samantha Schachermeyer, Wenwan Zhong
    Pages 127-138
  10. Kelly A Barton, Valerie L Sim, Andrew G Hughson, Byron Caughey
    Pages 139-149
  11. Karin D. Caldwell, Karin Fromell
    Pages 151-164
  12. Lars Nilsson
    Pages 165-185
  13. Susanne K. Wiedmer, Gebrenegus Yohannes
    Pages 207-221
  14. G. Bégaud-Grimaud, S. Battu, D. Leger, P. J. P. Cardot
    Pages 223-253
  15. Back Matter
    Pages 301-305

About this book


This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most commonly used solvent systems. Importantly, the field-flow fractionation (FFF) technique has recently emerged as a prominent complement to size exclusion chromatography for protein pharmaceuticals. Fractionation with FFF is gentle and preserves protein structural integrity better than existing alternatives. In the present text, different chapters are written by experts in their respective field of application, who offer comparisons between the FFF techniques and other methods for characterizing their special focus material. Practical guide-lines for successful implementation, such as choice of operating conditions, are offered in conjunction with each application. In addition to new instrumentation and approaches that address important current topics, readers are provided with an overall sense of prior (but timeless) major developments that may be overlooked in literature searches.




FFF biopolymer analysis field flow fractionation natural polymers separation

Editors and affiliations

  • S. Kim R. Williams
    • 1
  • Karin D. Caldwell
    • 2
  1. 1.Golden ColoradoUSA
  2. 2.UppsalaSweden

Bibliographic information

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