Advertisement

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, Vol. 93

  • Mahendra Sahai
  • Edda Gössinger
  • Marta Luzhetska
  • Johannes Härle
  • Sajeli A. Begum
  • Anil B. Ray
  • A. Douglas Kinghorn
  • Heinz Falk
  • Junichi Kobayashi

Table of contents

  1. Front Matter
    Pages i-xv
  2. Sajeli A. Begum, Mahendra Sahai, Anil B. Ray
    Pages 1-70
  3. Edda Gössinger
    Pages 71-210
  4. Marta Luzhetska, Johannes Härle, Andreas Bechthold
    Pages 211-237
  5. Back Matter
    Pages 239-264

About this book

Introduction

Lignans, by convention, are a group of natural products that are formed by linking two phenylpropanoid units (C C units) by oxidative coupling. Most importantly, in 6 3 a lignan, two (C C units) are bound through the central carbon of their side chains, 6 3 0 i. e. the 8 and 8 positions (1, 2). The occurrence of C C -dimers, linked at sites other 6 3 0 than the 8–8 positions, is also known and these compounds have been termed neolignans (3, 4). As these two groups of compounds have close structural as well as biosynthetic relationships, they are often associated together and incorporated under the general term “lignan” (5). The diverse structural categorization of true lignans and of a few neolignans is presented in Fig. 1. Through the years, several review articles or books covering different facets of lignans, including their ch- istry (6, 7), biogenesis (8), synthesis (9), and biological activities (10) have been published. Enduring research for the investigation of secondary metabolites of plants has evidenced some compounds that are biogenetically related to true lignans or neolignans but bear some features not discerned in conventional lignans. These compounds or groups of compounds have been termed as “non-conventional lignans”, and include coumarinolignans, ?avonolignans, and stilbenolignans. The non-conventional lignans, like the conventional ones, have two C C units linked 6 3 together but have additional structural features to place them also under the category of coumarins, ?avonoids, or stilbenes.

Keywords

biochemistry chemistry natural product polymer synthesis

Authors and affiliations

  • Mahendra Sahai
    • 1
  • Edda Gössinger
    • 2
  • Marta Luzhetska
    • 3
  • Johannes Härle
    • 4
  • Sajeli A. Begum
    • 5
  • Anil B. Ray
    • 6
  1. 1.Inst. Medical Sciences, Dept. Medicinal ChemistryBanaras Hindu UniversityVaranasiIndia
  2. 2.Inst. Organische ChemieUniversität WienWienAustria
  3. 3.Inst. Pharmazeutische Wissenschaften, LS für Pharmazeutische Biologie undUniversität FreiburgFreiburgGermany
  4. 4.Inst. Pharmazeutische Wissenschaften, LS für Pharmazeutische Biologie undUniversität FreiburgFreiburgGermany
  5. 5.Inst. Medical Sciences, Dept. Medicinal ChemistryBanaras Hindu UniversityVaranasiIndia
  6. 6.Inst. Medical Sciences, Dept. Medicinal ChemistryBanaras Hindu UniversityVaranasiIndia

Editors and affiliations

  • A. Douglas Kinghorn
    • Heinz Falk
      • Junichi Kobayashi

        There are no affiliations available

        Bibliographic information

        Industry Sectors
        Pharma
        Chemical Manufacturing
        Biotechnology
        Consumer Packaged Goods