Cellular Dedifferentiation and Regenerative Medicine

  • Xiaobing Fu
  • Andong Zhao
  • Tian Hu
Book

Table of contents

  1. Front Matter
    Pages i-xii
  2. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 1-17
  3. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 19-37
  4. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 39-64
  5. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 65-90
  6. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 91-116
  7. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 117-131
  8. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 133-162
  9. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 163-173
  10. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 175-193
  11. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 195-245
  12. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 247-271
  13. Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 273-280
  14. Back Matter
    Pages 281-291

About this book

Introduction

This book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications.

The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine.

The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.

Keywords

Dedifferentiation Development of Cancer Mammalian tissue cells Peripheral nerve regeneration Skin regeneration

Authors and affiliations

  • Xiaobing Fu
    • 1
  • Andong Zhao
    • 2
  • Tian Hu
    • 3
  1. 1.Key Laboratory of Wound Repair and Regeneration of PLAThe First Hospital Affiliated to the PLA General HospitalBeijingChina
  2. 2.Tianjin Medical UniversityTianjinChina
  3. 3.School of MedicineNankai UniversityTianjinChina

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-56179-9
  • Copyright Information Springer-Verlag GmbH Germany 2018
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-662-56177-5
  • Online ISBN 978-3-662-56179-9
  • About this book
Industry Sectors
Pharma