Genome Mapping and Genomics in Human and Non-Human Primates

  • Ravindranath Duggirala
  • Laura Almasy
  • Sarah Williams-Blangero
  • Solomon F.D. Paul
  • Chittaranjan Kole

Part of the Genome Mapping and Genomics in Animals book series (MAPPANIMAL, volume 5)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Sarah Williams-Blangero, John Blangero
    Pages 1-6
  3. Satish Kumar, Christopher Kingsley, Johanna K. DiStefano
    Pages 7-31
  4. Laura Almasy, Mark Zlojutro Kos, John Blangero
    Pages 33-52
  5. Robert L. Hanson, Alka Malhotra
    Pages 53-66
  6. Harald H.H. Göring
    Pages 67-83
  7. August N. Blackburn, Donna M. Lehman
    Pages 85-101
  8. Braxton D. Mitchell, Alejandro A. Schäffer, Toni I. Pollin, Elizabeth A. Streeten, Richard B. Horenstein, Nanette I. Steinle et al.
    Pages 141-153
  9. Jean W. MacCluer, John Blangero, Anthony G. Comuzzie, Sven O. E. Ebbesson, Barbara V. Howard, Shelley A. Cole
    Pages 155-179
  10. Rector Arya, Sobha Puppala, Vidya S. Farook, Geetha Chittoor, Christopher P. Jenkinson, John Blangero et al.
    Pages 181-245
  11. D. Reese McKay, Anderson M. Winkler, Peter Kochunov, Emma E.M. Knowles, Emma Sprooten, Peter T. Fox et al.
    Pages 247-258
  12. Richard J. Sherwood, Dana L. Duren
    Pages 259-275
  13. Julia N. Bailey, Christopher Patterson, Lynn A. Fairbanks
    Pages 277-288
  14. Joanne E. Curran, Claire Bellis, Laura Almasy, John Blangero
    Pages 289-299
  15. Back Matter
    Pages 301-305

About this book

Introduction

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented.

Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.

Keywords

Disease-Related Genes Epidemiology of Aleutian island populations Genetics of cardiovascular diseases Human Genome Project Linkage Mapping Primate craniofacial complex Statistical genetics Transcriptomics

Editors and affiliations

  • Ravindranath Duggirala
    • 1
  • Laura Almasy
    • 2
  • Sarah Williams-Blangero
    • 3
  • Solomon F.D. Paul
    • 4
  • Chittaranjan Kole
    • 5
  1. 1.South Texas Diabetes and Obesity InstituteUniversity of Texas Health Science Center at San AntonioEdinburgUSA
  2. 2.South Texas Diabetes and Obesity InstituteUniversity of Texas Health Science Center at San AntonioSan AntonioUSA
  3. 3.South Texas Diabetes and Obesity InstituteBrownsvilleUSA
  4. 4.Faculty of Biomedical Sciences, Technology & ResearchSri Ramachandra UniversityChennaiIndia
  5. 5.Bidhan Chandra Krishi ViswavidyalayaMohanpurIndia

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-46306-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 2015
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-662-46305-5
  • Online ISBN 978-3-662-46306-2
  • About this book