Editors:
- Presents an in-depth and global analysis of how IL-10 contributes to immunity
- Offers a set of reviews dedicated to the biology of IL-10
- Provides a comprehensive overview on one of the most important anti-inflammatory cytokines
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 380)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
About this book
This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.
Editors and Affiliations
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Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany
Simon Fillatreau
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Div. of Immunoregulation, The MRC National Institute for Medical Research, London, United Kingdom
Anne O'Garra
Bibliographic Information
Book Title: Interleukin-10 in Health and Disease
Editors: Simon Fillatreau, Anne O'Garra
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-662-43492-5
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2014
Hardcover ISBN: 978-3-662-43491-8Published: 28 July 2014
Softcover ISBN: 978-3-662-52405-3Published: 23 August 2016
eBook ISBN: 978-3-662-43492-5Published: 08 July 2014
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VIII, 238
Number of Illustrations: 16 illustrations in colour
Topics: Immunology, Cytokines and Growth Factors, Molecular Medicine
Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma