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Myocardial Preconditioning

  • Book
  • © 1996

Overview

Authors:
  1. Cherry L. Wainwright

    1. Department of Physiology and Pharmacology, University of Strathclyde, Royal College, Glasgow, Scotland

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  2. James R. Parratt

    1. Department of Physiology and Pharmacology, University of Strathclyde, Royal College, Glasgow, Scotland

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    You can also search for this author in PubMed   Google Scholar

Part of the book series: Medical Intelligence Unit (MIU.LANDES)

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Table of contents (15 chapters)

  1. Front Matter

    Pages N2-XIII
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  2. Preconditioning Against Myocardial Infarction—Its Features and Adenosine-Mediated Mechanism

    • Tetsuji Miura
    Pages 1-17

  3. Does Preconditioning Reduce Lethal Mechanical Reperfusion Injury?

    • David García-Dorado, Marisol Ruiz-Meana, José A. Barrabés
    Pages 19-34

  4. Ischemic Preconditioning Markedly Reduces the Severity of Ischemia and Reperfusion-Induced Arrhythmias: Role of Endogenous Myocardial Protective Substances

    • Agnes Vegh, James R. Parratt
    Pages 35-60

  5. The Protective Effects of Preconditioning on Postischemic Contractile Dysfunction

    • Alison C. Cave
    Pages 61-78

  6. Reduction of Infarct Size— “Preconditioning at a Distance”

    • Karin Przyklenk, Peter Whittaker, Michel Ovize, Robert A. Kloner
    Pages 79-96

  7. Novel Approaches to Myocardial Preconditioning in Pigs

    • Ben C. G. Gho, Monique M. G. Koning, René L. J. Opstal, Eric van Klaarwater, Dirk J. Duncker, Pieter D. Verdouw
    Pages 97-113

  8. Preconditioning in the Human Heart: Fact or Fantasy?

    • Clive S. Lawson
    Pages 115-128

  9. Role of ATP-Sensitive Potassium Channels in Myocardial Preconditioning

    • Gary J. Grover
    Pages 129-146

  10. The Role of G Proteins in Myocardial Preconditioning

    • Lucia Piacentini, Nigel J. Pyne
    Pages 147-166

  11. Mimicking Preconditioning with Catecholamines

    • Tanya Ravingerová
    Pages 167-184

  12. Activation of Protein Kinase C is Critical to the Protection of Preconditioning

    • Michael V. Cohen, Yongge Liu, James M. Downey
    Pages 185-206

  13. The Mechanism of Preconditioning—What Have We Learned from the Different Animal Species?

    • Cherry L. Wainwright, Wei Sun
    Pages 207-232

  14. Myocardial Stress Response, Cytoprotective Proteins and the Second Window of Protection Against Infarction

    • Gary F. Baxter, Michael S. Marber, Derek M. Yellon
    Pages 233-250

  15. Delayed Ischemic Preconditioning Induced by Drugs and by Cardiac Pacing

    • Agnes Vegh, James R. Parratt
    Pages 251-260

  16. Cardioprotective Effects of Chronic Hypoxia: Relation to Preconditioning

    • František Kolář
    Pages 261-275

  17. Back Matter

    Pages 277-285
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Keywords

About this book

This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium - a phenomenon which is switched on by stress and termed myocardial preconditioning. This volume describes the main features and characteristics of preconditioning, with respect to the time-course of the protective effect of the phenomenon (first and second windows) and the different sequelae of myocardial ischaemia against which it protects, such as myocardial injury, arrhythmias and contractile dysfunction. The proposed mechanisms underlying the fascinating form of cardioprotection are discussed. Among these are the role of endogenous labile mediators, receptor-linked G proteins, ATP-sensitive potassium channels and protein kinase C activation.

Authors and Affiliations

  • Department of Physiology and Pharmacology, University of Strathclyde, Royal College, Glasgow, Scotland

    Cherry L. Wainwright, James R. Parratt

Bibliographic Information

  • Book Title: Myocardial Preconditioning

  • Authors: Cherry L. Wainwright, James R. Parratt

  • Series Title: Medical Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-22206-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1996

  • Softcover ISBN: 978-3-662-22208-9Published: 20 November 2013

  • eBook ISBN: 978-3-662-22206-5Published: 22 November 2013

  • Series ISSN: 1080-3645

  • Edition Number: 1

  • Number of Pages: XIII, 285

  • Additional Information: Jointly published with R.G. Landes, Biomedical Publishers, Austin, USA

  • Topics: Cell Biology

  • Industry Sectors: Biotechnology, Pharma

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