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Preclinical Hyperthermia

  • Conference proceedings
  • © 1988

Overview

Editors:
  1. Wolfgang Hinkelbein

    1. Abteilung Strahlentherapie (Med. Klinik) Radiologische Klinik, Albert-Ludwigs-Universität, Freiburg, Germany

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  2. Gregor Bruggmoser

    1. Abteilung Strahlentherapie (Med. Klinik) Radiologische Klinik, Albert-Ludwigs-Universität, Freiburg, Germany

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  3. Rupert Engelhardt

    1. Abteilung Strahlentherapie (Med. Klinik) Radiologische Klinik, Albert-Ludwigs-Universität, Freiburg, Germany

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  4. Michael Wannenmacher

    1. Abteilung Strahlentherapie (Med. Klinik) Radiologische Klinik, Albert-Ludwigs-Universität, Freiburg, Germany

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 109)

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Table of contents (27 papers)

  1. Front Matter

    Pages I-XI
    Download chapter PDF

  2. Modification of Heat Action and Thermal Enhancement of Radio- and Chemotherapy

    1. Hyperthermic Toxicity and the Modulation of Heat Damage to Cell Protein Synthesis in HeLa Cells

      • R. H. Burdon
      Pages 1-8

    2. Membranes as Targets for Hyperthermic Cell Killing

      • A. W. T. Konings
      Pages 9-21

    3. Sulfhydryl Compounds as Thermosensitizers

      • R. D. Issels
      Pages 22-27

    4. Therapeutic Benefit from Combined Heat and Radiation

      • S. A. Hill, J. Denekamp
      Pages 28-34

    5. Correlation Between Polymerase ß Activity and Thermal Radiosensitization in Chinese Hamster Ovary Cells

      • E. Dikomey, H. Jung
      Pages 35-41

  3. Effect of Heat and Combined Treatments on Normal Tissues

    1. The Problem of Defining Thermal Dose

      • M. P. Law, S. B. Field
      Pages 42-49

    2. Effect of Hyperthermia on Human Natural Killer Cells

      • M. Onsrud
      Pages 50-56

    3. Effect of Hyperthermia at 40.5° C and Cytostatic Drugs on Human Bone Marrow Progenitor Cells

      • H. A. Neumann, R. Engelhardt
      Pages 57-63

    4. Combined Heat and X-Ray Toxicities in Intestine and Skin

      • S. P. Hume
      Pages 64-70

    5. Toxic Effects of Irradiation or Doxorubicin in Combination with Moderate Whole-Body Hyperthermia on Bone Marrow in Rats

      • W. Hinkelbein, M. Birmelin, D. Menger, R. Engelhardt
      Pages 71-82

    6. Cardiotoxicity of Moderate Whole-Body Hyperthermia, Doxorubicin, and Combined Treatment in Rats

      • M. Birmelin, W. Hinkelbein, W. Oehlert, M. Wannenmacher
      Pages 83-88

  4. Preclinical Hpyerthermia in Animal Tumors and Malignant Cell Lines

    1. Effects of Hyperthermic Treatments on Malignant Cells and Animal Tumors: Introductory Remarks

      • C. Streffer
      Pages 89-95

    2. Hyperthermia and Microcirculatory Effects of Heat in Animal Tumors

      • B. Endrich
      Pages 96-108

    3. Importance of the Glutathione Level and the Activity of the Pentose Phosphate Pathway in Cellular Heat Sensitivity

      • A. W. T. Konings
      Pages 109-125

    4. Potentiation of Hyperthermia by Lanthanum

      • L. Anghileri
      Pages 126-135

    5. Interactions of Hyperthermia with Hypoxic Cell Sensitisers

      • N. M. Bleehen, M. I. Walton, P. Workman
      Pages 136-148

    6. Thermal Enhancement of the Cell Killing Effect of X-Irradiation in Mammalian Cells in Vitro and in a Transplantable Mouse Tumor: Influence of pH, Thermotolerance, Hypoxia, or Misonidazole

      • J. Haveman, J. Wondergem
      Pages 149-160

    7. Thermal Enhancement of Drug Cytotoxicity in Vivo and in Vitro

      • D. J. Honess, N. M. Bleehen
      Pages 161-169

  5. Effect of Heat and Combined Treatments on Human Tumors

    1. Preclinical Hyperthermia in Human Tumors: Introductory Remarks

      • R. Engelhardt
      Pages 170-172
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Keywords

About this book

Physicians and biologists here present their experimental work in the field of hyperthermia, paying particular regard to its relevance in clinical situations. Principles of heat action and combined treatment modalities are explicated. The main topics discussed are the effects of such treatment on normal tissues, animal tumors, malignant cell lines and human tumors.

Editors and Affiliations

  • Abteilung Strahlentherapie (Med. Klinik) Radiologische Klinik, Albert-Ludwigs-Universität, Freiburg, Germany

    Wolfgang Hinkelbein, Gregor Bruggmoser, Rupert Engelhardt, Michael Wannenmacher

Bibliographic Information

  • Book Title: Preclinical Hyperthermia

  • Editors: Wolfgang Hinkelbein, Gregor Bruggmoser, Rupert Engelhardt, Michael Wannenmacher

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-83263-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-3-642-83265-9Published: 09 February 2012

  • eBook ISBN: 978-3-642-83263-5Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XII, 262

  • Topics: Oncology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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