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The Human Thymus

Histophysiology and Pathology

  • Book
  • © 1986

Overview

Editors:
  1. Hans Konrad Müller-Hermelink

    1. Pathologisches Institut der Universität Würzburg, Luitpoldkrankenhaus, Würzburg, Germany

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Part of the book series: Current Topics in Pathology (CT PATHOLOGY, volume 75)

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Table of contents (7 chapters)

  1. Front Matter

    Pages I-IX
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  2. The Development of the Human Thymus Microenviroment

    • B. von Gaudecker
    Pages 1-41

  3. Changes in the Human Thymus During Aging

    • G. G. Steinmann
    Pages 43-88

  4. Cellular Differentiation of Lymphoid Subpopulations and Their Microenvironments in the Human Thymus

    • G. Janossy, M. Bofill, L. K. Trejdosiewicz, H. N. A. Willcox, M. Chilosi
    Pages 89-125

  5. Thymic Atrophy and Immune Deficiency in Malnutrition

    • N. Dourov
    Pages 127-150

  6. Pathology of the Thymus in Immunodeficiency States

    • Ch. Nezelof
    Pages 151-177

  7. The Thymus in Myasthenia Gravis

    • H. Wekerle, H. K. Müller-Hermelink
    Pages 179-206

  8. Pathology of Thymic Epithelial Tumors

    • H. K. Müller-Hermelink, M. Marino, G. Palestro
    Pages 207-268

  9. Back Matter

    Pages 269-278
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Keywords

About this book

Twenty-five years have passed since J. MILLER'S basic work on the central role of the thymus for the generation of immunological reactivi­ ty. During this time, the abundance of fascinating literature on the immunological and functional aspects of this organ has been in contrast to the paucity of reports on its role in pathology. The causal or formal pathogenesis even of many of the well-documented pathological fea­ tures is so far unexplained or at least uncertain. In spite of some concep­ tual progress related to the work of CASTLEMAN, LEVINE, and ROSAI, we regrettably have to say that in pathology the thymus remains almost as inconspicuous as 25 years ago. Only the new techniques developed in recent years have made it possible to look as closely into the complicated structural organization of the thymus as it appears to be necessary to observe and document abnormalities. Major steps have been taken with the advent of mono­ clonal antibody immune histochemistry and with detailed ultrastructur­ al studies in embryology. At this point, pathologists and researchers with a special interest in the thymus were asked to give overviews of their respective fields of interest in light of recent findings in immunology and basic insights into the structural-functional interrelationship of the human thymus. The results of this initiative have been brought together in this volume.

Editors and Affiliations

  • Pathologisches Institut der Universität Würzburg, Luitpoldkrankenhaus, Würzburg, Germany

    Hans Konrad Müller-Hermelink

Bibliographic Information

  • Book Title: The Human Thymus

  • Book Subtitle: Histophysiology and Pathology

  • Editors: Hans Konrad Müller-Hermelink

  • Series Title: Current Topics in Pathology

  • DOI: https://doi.org/10.1007/978-3-642-82480-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1986

  • Softcover ISBN: 978-3-642-82482-1Published: 10 January 2012

  • eBook ISBN: 978-3-642-82480-7Published: 06 December 2012

  • Series ISSN: 0070-2188

  • Edition Number: 1

  • Number of Pages: X, 278

  • Number of Illustrations: 85 b/w illustrations

  • Topics: Pathology

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

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