Skip to main content
SpringerLink
Log in

Gene Interactions in Development

  • Book
  • © 1981

Overview

Authors:
  1. L. I. Korochkin

    1. Institute of Developmental Biology, Moscow, USSR

    View author publications

    You can also search for this author in PubMed   Google Scholar

  2. A. Grossman

    1. Dept. of Biological Science, The Florida State University, Tallahassee, USA

    View author publications

    You can also search for this author in PubMed   Google Scholar

Part of the book series: Monographs on Theoretical and Applied Genetics (GENETICS, volume 4)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 16.99 USD 84.99
Discount applied Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (10 chapters)

  1. Front Matter

    Pages I-XIII
    Download chapter PDF

  2. Introduction

    1. Introduction

      • L. I. Korochkin, A. Grossman
      Pages 1-4

  3. Gene Interaction at the Cellular Level

    1. Front Matter

      Pages 5-5
      Download chapter PDF

    2. Differential Activity of Genes as a Basis for Cell Differentiation

      • L. I. Korochkin, A. Grossman
      Pages 7-48

    3. The Realization of Differential Gene Activity on the Post-Transcriptional, Translational, and Post-Translational Levels

      • L. I. Korochkin, A. Grossman
      Pages 49-107

    4. The Phenomenon of Allelic Exclusion

      • L. I. Korochkin, A. Grossman
      Pages 108-124

    5. Nuclear-Cytoplasmic Interactions. The Basis for the Regulation of Gene Activity

      • L. I. Korochkin, A. Grossman
      Pages 125-152

  4. Gene Interaction at the Tissue Level

    1. Front Matter

      Pages 153-153
      Download chapter PDF

    2. Functional-Genetic Mosaicism in Cell Population

      • L. I. Korochkin, A. Grossman
      Pages 155-172

    3. Genetic Heterogeneity and the Establishment of Tissue Systems During Development

      • L. I. Korochkin, A. Grossman
      Pages 173-208

    4. Genetic Regulation of Ontogenesis on the Organismal Level

      • L. I. Korochkin, A. Grossman
      Pages 209-232

    5. The Organization of Systems Which Control Differential Gene Expression

      • L. I. Korochkin, A. Grossman
      Pages 233-273

  5. Conclusion

    1. Conclusion

      • L. I. Korochkin, A. Grossman
      Pages 274-275

  6. Back Matter

    Pages 276-320
    Download chapter PDF
Back to top

Keywords

About this book

Since the Russian edition of this book was published in 1975 many new research works have appeared which have made necessary some additions for the English edition, to reflect progress in molecular developmental genetics. Recent important findings in this field have brought about essential corrections to the concept of genetic regulation of the process of cell differentiation. The discovery of the mosaic structure of a gene prompted the re­ evaluation of our considerations about the regulation of gene activity in eukaryotes, and the data about transcriptional events during ontogenesis are of great importance as well. Formerly it was generally accepted that a derepression of genes was responsible for cell differentiation in the process of develop­ ment. Recently three important conclusions have been derived (Davidson and Britten, 1979) which help to pose the problem in a new way: 1) Only a small part of single copy sequences of DNA is represented in nuclear RNA of a given type of cell or tissue: 10% to 20% in sea urchin embryos, 11 % in rat liver, 4% to 6% in Drosophila cell culture, etc. Since only about 10% of single copy sequences represent the structural genes (Davidson and Britten, 1973), transcription of almost the whole set of structural genes occurs.

Authors and Affiliations

  • Institute of Developmental Biology, Moscow, USSR

    L. I. Korochkin

  • Dept. of Biological Science, The Florida State University, Tallahassee, USA

    A. Grossman

Bibliographic Information

  • Book Title: Gene Interactions in Development

  • Authors: L. I. Korochkin, A. Grossman

  • Series Title: Monographs on Theoretical and Applied Genetics

  • DOI: https://doi.org/10.1007/978-3-642-81477-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin � Heidelberg 1981

  • Softcover ISBN: 978-3-642-81479-2Published: 19 January 2012

  • eBook ISBN: 978-3-642-81477-8Published: 06 December 2012

  • Series ISSN: 0341-5376

  • Edition Number: 1

  • Number of Pages: XIV, 320

  • Additional Information: Title of the original Russian edition: Vzaimodejstvie genov v razvitii

  • Topics: Cell Biology, Plant Sciences, Zoology

  • Industry Sectors: Biotechnology, Pharma

Publish with us

Policies and ethics

Back to top

Search

Navigation