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  • Book
  • © 1993

GTPases in Biology II

Editors:

  1. Burton F. Dickey

    1. Baylor College of Medicine, Department of Medicine Cell Biology and Experimental Therapeutics, Houston VA Medical Center, Houston, USA

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  2. Lutz Birnbaumer

    1. Department of Cell Biology, Molecular Physiology and Biophysics, Medicine and Neurosciences, Baylor College of Medicine, Houston, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 108 / 2)

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Table of contents (37 chapters)

  1. Front Matter

    Pages I-XL
    PDF

  2. Signal Transduction by Trimeric G Proteins

    1. Front Matter

      Pages 1-1
      PDF

    2. Cellular Architecture and its Role in Signal Transduction

    3. G-Protein Coupled Receptors

      1. The Superfamily: Molecular Modelling
        • J. B. C. Findlay, D. Donnelly
        Pages 17-31

    4. Trimeric G-Proteins

      4. The GTPase Cycle: Transducin
        • T. D. Ting, R. H. Lee, Y.-K. Ho
        Pages 99-117
      7. Phosphorylation of Heterotrimeric G-Protein
        • M. D. Houslay
        Pages 147-165

    5. Effectors of G-Proteins

      1. Molecular Diversity of Mammalian Adenylyl Cyclases: Functional Consequences
        • R. T. Premont, J. Chen, O. Jacobowitz, R. Iyengar
        Pages 189-212
      3. High-Voltage Activated Ca2+ Channel
        • F. Hofmann, M. Biel, E. Bosse, R. Hullin, P. Ruth, A. Welling et al.
        Pages 225-238

    6. Specialized Systems

      1. Rhodopsin/G-Protein Interaction
        • K. P. Hofmann
        Pages 267-290
      2. Fast Kinetics of G-Protein Function In Vivo
        • G. Szabo, Y. Li, A. S. Otero
        Pages 291-302
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About this book

Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches uti- lized intracellularly in biological systems. The origins of the GTPase switch appear to be almost as ancient as life it- self, and through evolution nature has adapted this switch to a variety of purposes. In this two-volume work a broad survey of the major classes of GTPases is presented. The role of GTPases in ensuring ac- curacy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer, are all described in 80 chapters by the leading authorities in their fields. Both detailed knowledge of specific systems or proteins and general principles of structure and function are offered. Much of this information has never been published before. At the rate the extended family of GTPases is growing it becomes increasingly unlikely that we will again get it to sit for a group portrait such as this. Therefore, the volume has the chance to become t h e reference work for GTPases.
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Keywords

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Editors and Affiliations

  • Baylor College of Medicine, Department of Medicine Cell Biology and Experimental Therapeutics, Houston VA Medical Center, Houston, USA

    Burton F. Dickey

  • Department of Cell Biology, Molecular Physiology and Biophysics, Medicine and Neurosciences, Baylor College of Medicine, Houston, USA

    Lutz Birnbaumer

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Bibliographic Information

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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