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Opioids I

  • Book
  • © 1993

Overview

Editors:
  1. Albert Herz

    1. Abteilung Neuropharmakologie, Max-Planck-Institut für Psychiatrie, Martinsried, Germany

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  2. Huda Akil

    1. Mental Health Research Institute, School of Medicine, University of Michigan, Ann Arbor, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Eric J. Simon

    1. Medical Center, School of Medicine, New York University, New York, USA

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Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 104 / 1)

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Table of contents (30 chapters)

  1. Opioid Peptides

    1. Proopiomelanocortin Biosynthesis, Processing, and Secretion: Functional Implications

      • E. Young, D. Bronstein, H. Akil
      Pages 393-421

    2. Biosynthesis of Enkephalins and Proenkephalin-Derived Peptides

      • J. Rossier
      Pages 423-447

    3. Prodynorphin Biosynthesis and Posttranslational Processing

      • R. Day, K. A. Trujillo, H. Akil
      Pages 449-470

    4. Anatomy and Function of the Endogenous Opioid Systems

      • H. Khachaturian, M. K. H. Schaefer, M. E. Lewis
      Pages 471-497

    5. Atypical Opioid Peptides

      • H. Teschemacher
      Pages 499-528

    6. Opioid Peptide Processing Enzymes

      • L. D. Fricker
      Pages 529-545

    7. Peptidase Inactivation of Enkephalins: Design of Inhibitors and Biochemical, Pharmacological, and Clinical Applications

      • B. P. Roques, A. Beaumont, V. Dauge, M.-C. Fournié-Zaluski
      Pages 547-584

    8. Coexistence of Opioid Peptides with Other Neurotransmitters

      • R. Elde, T. Hökfelt
      Pages 585-624

    9. Interrelationships of Opioid, Dopaminergic, Cholinergic, and GABAergic Pathways in the Central Nervous System

      • P. L. Wood
      Pages 625-643

    10. Selectivity of Ligands for Opioid Receptors

      • A. D. Corbett, S. J. Paterson, H. W. Kosterlitz
      Pages 645-679

    11. Development of Receptor-Selective Opioid Peptide Analogs as Pharmacologic Tools and as Potential Drugs

      • P. W. Schiller
      Pages 681-710

    12. Ontogeny of Mammalian Opioid Systems

      • J. E. Pintar, R. E. M. Scott
      Pages 711-727

  2. Neurophysiology

    1. Front Matter

      Pages 729-729
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    2. Opioids and Sensory Processing in the Central Nervous System

      • A. W. Duggan, S. M. Fleetwood-Walker
      Pages 731-771

    3. Opioid Actions on Membrane Ion Channels

      • R. A. North
      Pages 773-797

  3. Back Matter

    Pages 799-815
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Keywords

About this book

In 1957 Otto SCHAUMANN, one of the pionieers in pharmacological research on morphine and the first to prepare synthetic opiates, presented a mono­ graph entitled "Morphin und morphiniihnliche Verbindungen" as Volume 12 of the Handbook of Experimental Pharmacology. Now, 35 years later, we are publishing in the same series a new comprehensive volume covering the present status of opioid research. Since that time the topic has expanded enormously. The identification of opioid receptors and the detection of their endogenous ligands were landmarks which opened a new era in opioid research and fertilized the entire field of neurobiology. The rapid develop­ ment of this field is illustrated in the figure, which represents the number of papers published on opioid research since 1970 (searches performed on the MEDLINE data base). 3000 Vl

Editors and Affiliations

  • Abteilung Neuropharmakologie, Max-Planck-Institut für Psychiatrie, Martinsried, Germany

    Albert Herz

  • Mental Health Research Institute, School of Medicine, University of Michigan, Ann Arbor, USA

    Huda Akil

  • Medical Center, School of Medicine, New York University, New York, USA

    Eric J. Simon

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