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Advances in Controlled Clinical Inhalation Studies

  • Conference proceedings
  • © 1993

Overview

Editors:
  1. Ulrich Mohr

    1. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Hannover 61, Germany

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  2. David V. Bates

    1. Dept. Health and Epidemiology, University of British Columbia, Vancouver, Canada

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  3. H. Fabel

    1. Abteilung Pneumologie, Medizinische Hochschule Hannover, Hannover 61, Germany

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  4. Mark J. Utell

    1. Pulmonary and Critical Care Unit, University of Rochester Medical Center, Rochester, USA

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Part of the book series: ILSI Monographs (ILSI MONOGRAPHS)

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Table of contents (42 papers)

  1. Front Matter

    Pages I-XII
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  2. Symposium Presentation

    1. Front Matter

      Pages 1-1
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    2. The Emergence of Controlled Human Exposure Studies

      • D. V. Bates
      Pages 3-7

    4. The Outdoor Environment in North America

      1. Exposure to Oxidant Gases and Acidic Particles in the United States
        • P. J. Lioy
        Pages 31-42

    6. Assessing Personal Exposure

      1. Personal Exposure Assessment: Implications for Clinical Studies of Inhaled Pollutants
        • J. M. Samet, W. E. Lambert
        Pages 95-101
      2. Regional Deposition of Inhaled Particles in the Human Respiratory Tract
        • J. Heyder
        Pages 103-107
      3. Calculation of Acid Aerosol Dose
        • T. V. Larson, Q. S. Hanley, J. Q. Koenig, O. Bernstein
        Pages 109-121

    8. New Methodologies

      1. Controlled Clinical Inhalation Studies with Environmental Air Pollutants at Concentrations Commonly Found in the Ambient Air
        • T. O. F. Wagner, W. H. T. Schürmann, H. Fabel
        Pages 159-167
      2. Time- and Dose-Dependent Cellular and Biochemical Changes in Response to Ozone Exposure
        • H. S. Koren, S. Becker, P. A. Bromberg, R. B. Devlin
        Pages 169-183
      3. Regeneration, Differentiation, and Neoplastic Transformation of Type II Alveolar Epithelial Cells
        • K.-U. Thiedemann, I. Paulini, N. Lüthe, A. Kreft, U. Abel, U. Heinrich et al.
        Pages 185-197
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Keywords

About this book

Advances in Controlled Clinical Inhalation Studies represents scientific work presented at the 3rd International Inhalation Symposium held 1991 in Hannover, FRG. The symposium covered the new developments in this field of research. The main pollutants of interest were acid aerosols, fog, and indoor pollutants, while with regard to biological effects, an emphasis was placed on immunotoxicological and biochemical parameters. Tests on high risk groups were also considered. Initial chapters describe the outdoor environment as well as indoor air, measurement and quality - both at home and in the workplace. Besides methods for clinical inhalation and assessing personal exposure, new methodologies are particularly presented. Further chapters focus on the relevance of clinical data for regulatory decisions.

Editors and Affiliations

  • Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Hannover 61, Germany

    Ulrich Mohr

  • Dept. Health and Epidemiology, University of British Columbia, Vancouver, Canada

    David V. Bates

  • Abteilung Pneumologie, Medizinische Hochschule Hannover, Hannover 61, Germany

    H. Fabel

  • Pulmonary and Critical Care Unit, University of Rochester Medical Center, Rochester, USA

    Mark J. Utell

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