Current Topics in Biomedical Research

1. Front Matter

   Pages I-XI

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2. Paul Ehrlich in His Time: A Historian’s View

   • F. Stern

   Pages 1-9

3. The Dawn of Immunology: The Era of Paul Ehrlich

   • O. Westphal

   Pages 11-34

4. Soluble Lymphocyte Receptors

   • M. Schlesinger

   Pages 35-51

5. Structure and Function of Antigen Receptor Complexes on Murine B Lymphocytes

   • D. Haustein

   Pages 53-64

6. The Biology of Mammary Cancer

   • R. Dulbecco

   Pages 65-73

7. Virus Quasispecies

   • M. Eigen

   Pages 75-77

8. Retroviruses: Nature’s Genetic Engineers

   • M. Temin

   Pages 79-84

9. Retroviruses and Autoimmunity

   • J. R. Kalden

   Pages 85-94

10. Genetic Control of De Novo Conversion to Infectious Amyloids of Host Precursor Proteins: Kuru-CJD-Scrapie

    • D. Carleton Gajdusek

    Pages 95-123

11. How Vaccines Work: Different Patterns for Different Diseases

    • J. Salk

    Pages 125-131

12. The Future of Immunological Drugs

    • H. G. Schwick

    Pages 133-144

13. Vaccines in Perspective: Human Hepatitis B Vaccines, the First Subunit and Recombinant Viral Vaccines

    • R. Hilleman

    Pages 145-161

14. Immunopathogenesis of HIV/SIV Infections: Consequences for the Development of AIDS Vaccines

    • R. Kurth, J. Ennen, J. Denner, S. Hartung, D. Binninger, M. Vogel et al.

    Pages 163-177

15. Back Matter

    Pages 179-185

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A select group of highly renowned scientists - among them four Nobel Prize Winners - have been asked to summarize significant developments of their ownrecent research in the life sciences at a workshop organized on the occasionof the opening of the new Paul-Ehrlich-Institut in Langen near Frankfurt/ Main. They do this in a comparative fashion evaluating similar achievements in adjacent fields. Their intellectual state-of-the-art analysis and fascinating outlook on future perspectives provides exciting and stimulating reading. The authors address areas in virology, immunology, oncology and evolution. Intelligent design of vaccines and other immunologial drugs, virus evolution and viruses as nature's engineers, pathology of chronic autoimmune and central nervous system diseases and the biology of mammary cancer belong to the topics discussed. A book easy to read for scientists, doctors and students interested in rapidly developing fields in the life sciences.

• design
• development
• drugs
• engine
• future
• immunology
• oncology
• reading
• research
• vaccine

• Paul-Ehrlich-Institut, Bundesamt für Sera und Impfstoffe, Langen, Germany

  Reinhard Kurth, Walter K. Schwerdtfeger

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