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Lectins and Cancer

  • Conference proceedings
  • © 1991

Overview

Editors:
  1. Hans Joachim Gabius

    1. Max-Planck-Institut für experimentelle Medizin, Göttingen, Germany

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  2. Sigrun Gabius

    1. Abteilung Hämatologie/Onkologie, Medizinische Universitätsklinik, Göttingen, Germany

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Table of contents (23 papers)

  1. Front Matter

    Pages I-X
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  2. Molecular basis of lectin-carbohydrate interactions

    • N. Sharon
    Pages 1-12

  3. Invertebrate lectins: new aspects in retrospects

    • G. Uhlenbruck, F. G. Hanisch, W. E. G. Müller
    Pages 13-26

  4. Narcissus and Gerardia lectins: Tools for the development of a vaccine against AIDS and a new ELISA to quantify HIV-gp 120

    • W. E. G. Müller, J. M. S. Forrest, S.-H. Chang, B. E. Weiler, H. Schäcke, E. Matthes et al.
    Pages 27-40

  5. Lectin histochemistry of human thyroid tumors

    • I. Damjanov, M. Sobrinho-Simoes
    Pages 41-51

  6. Neoglycoconjugates: Fundamentals and recent progresses

    • Y. C. Lee, R. T. Lee
    Pages 53-69

  7. Neoglycoproteins and lectins in human lung cancer: A survey

    • K. Kayser, H.-J. Gabius
    Pages 71-84

  8. How to localize β-galactoside-specific endogenous lectins and their ligands in tissue sections: A comparison of the application of different histochemical tools in breast cancer

    • A. Schauer, S. Gabius, U. Brinck, H.-J. Gabius
    Pages 85-103

  9. Endogenous receptors fore carbohydrate ligands in human renal cell carcinoma (RCC)

    • R. Heicappell, H. Buszello, S. Gabius, R. Ackermann, H.-J. Gabius
    Pages 105-122

  10. Brain, nerves and muscles: Neoglycoproteins in the practice of neuromorphology and neuropathology

    • A. Bardosi, D. Brkovic, H.-J. Gabius
    Pages 123-135

  11. Site-associated differences in endogenous lectin expression by mouse colon carcinoma cells

    • D. Glaves, L. Weiss, F. Vidal-Vanaclocha
    Pages 137-152

  12. Differentiation-associated modulation of lactoside binding lectins in cancer cells

    • R. Lotan
    Pages 153-170

  13. Change in metastasis and organotropism of mouse lymphoma variants associated with changes in expression of adhesion molecules and chemotactic responsiveness

    • V. Schirrmacher, A. Kowitz, G. Kadmon, R. Benke, P. Altevogt
    Pages 171-178

  14. Biomodulation: An integrated approach to access and manipulate biological information

    • P. L. Mann, D. Eshima, D. M. Bitner, R. H. Griffey, R. Wenk, J. L. Born et al.
    Pages 179-206

  15. Immunotherapeutic effects of purified mistletoe lectin (ML-I) on murine large cell lymphoma

    • S. S. Joshi, K. C. Komanduri, S. Gabius, H.-J. Gabius
    Pages 207-216

  16. The rationale of mitogenic lectin therapy for cancer

    • B. M. Wimer
    Pages 217-228

  17. New perspectives in the treatment of acute myeloid leukemia by hematopoietic growth factors

    • W. Hiddemann, B. Wörmann, M. Zühlsdorf, C. Reuter, E. Schleyer, C. Busemann et al.
    Pages 229-235

  18. Enzyme replacement therapy with macrophage-targeted human placental glucocerebrosidase in Gaucher disease

    • R. O. Brady, N. W. Barton
    Pages 237-250

  19. Preparation of neoglycoprotein-bearing liposomes and their interaction with cells and tissues

    • N. Yamazaki, S. Kojima, S. Gabius, H.-J. Gabius
    Pages 251-261

  20. Membrane recognition of steroid-glycoprotein complexes: A model for steroid delivery to the target cells

    • G. V. Avvakumov
    Pages 263-272
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Keywords

About this book

Molecular recognition undoubtedly governs any aspect of cellular interaction. To understand tumor cell growth regulation and spread, analysisof protein carbohydrate interactions can contribute to lead to the establishment of rational methods for diagnosis and therapy. Chemically and biochemically optimized preparation of adequate tools, their application for localization of receptor (tissue lectin) and ligand (cellular glycoconjugate) pairs in tumor cells and tumor sections and the usefulness of a lectin from a plant extract as potent immunomodulator indicate the prospect for a place of such techniques in pathology and oncology.

Editors and Affiliations

  • Max-Planck-Institut für experimentelle Medizin, Göttingen, Germany

    Hans Joachim Gabius

  • Abteilung Hämatologie/Onkologie, Medizinische Universitätsklinik, Göttingen, Germany

    Sigrun Gabius

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