Chemical Carcinogenesis and Mutagenesis I

  • Colin S. Cooper
  • Philip L. Grover

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 94 / 1)

Table of contents

  1. Front Matter
    Pages I-XXVIII
  2. Theories of Carcinogenesis

  3. Exposure to Chemical Carcinogens

    1. Front Matter
      Pages 31-31
    2. K. Hemminki
      Pages 33-61
    3. D. Hoffmann, S. S. Hecht
      Pages 63-102
    4. C. E. Searle, O. J. Teale
      Pages 103-151
    5. D. B. Ludlum
      Pages 153-175
  4. In Vivo and In Vitro Carcinogenesis

    1. Front Matter
      Pages 177-177
    2. W. Lijinsky
      Pages 179-209
    3. M. A. Knowles
      Pages 211-264
  5. Reactions of Carcinogens with DNA

  6. Back Matter
    Pages 573-604

About this book

Introduction

I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin­ Madison. I immediately started to work with the carcinogenic aminoazo dyes un­ der the direction of Professor CARL BAUMANN. In 1942 I joined a fellow graduate student, ELIZABE1H CAVERT, in marriage and we soon commenced a joyous part­ nership in research on chemical carcinogenesis at the McArdle Laboratory for Cancer Research in the University of Wisconsin Medical School in Madison. This collaboration lasted 45 years. I am very grateful that this volume is dedi­ cated to the memory of Elizabeth. The important and varied topics that are reviewed here attest to the continued growth of the fields of chemical car­ cinogenesis and mutagenesis, including their recent and fruitful union with viral oncology. I feel very optimistic about the application of knowledge in these fields to the eventual solution of numerous problems, including the detection and estimation of the risks to humans of environmental chemical carcinogens and re­ lated factors.

Keywords

Carcinom DNA Mutagene Onkogene Viren cancer cancer research carcinogenesis cellular differentiation mutagen mutagenesis oncogene oncogenes research

Editors and affiliations

  • Colin S. Cooper
    • 1
  • Philip L. Grover
    • 1
  1. 1.Chester Beatty LaboratoriesThe Institute of Cancer Research: Royal Cancer HospitalLondonGreat Britain

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-74775-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-74777-9
  • Online ISBN 978-3-642-74775-5
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • About this book
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