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  • Conference proceedings
  • © 1988

The Calcium Channel: Structure, Function and Implications

Stresa/Italy, May 11–14, 1988

Editors:

  1. Martin Morad

    1. Department of Physiology, University of Pennsylvania, Philadelphia, USA

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  2. Winifred G. Nayler

    1. Department of Medicine, Austin Hospital, University of Melbourne, Heidelberg, Australia

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    You can also search for this editor in PubMed   Google Scholar

  3. Stanislav Kazda

    1. Bayer AG, Institute of Pharmacology, Wuppertal 1, Germany

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    You can also search for this editor in PubMed   Google Scholar

  4. Matthias Schramm

    1. Bayer AG, Institute of Pharmacology, Wuppertal 1, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Bayer AG Centenary Symposium (BAYER)

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Table of contents (51 papers)

  1. Front Matter

    Pages I-XXVII
    PDF

  2. History and Philosophy of Bayer Pharmaceutical Research

  3. The Effect of Lime and Potash on the Frog Heart: An Imaginative Reconstruction of a Paper Presented by Sydney Ringer to the Physiological Society on 9th December 1882

  4. Homology of Calcium-Modulated Proteins: Their Evolutionary and Functional Relationships

    1. Homology of Calcium-Modulated Proteins: Their Evolutionary and Functional Relationships

      • R. H. Kretsinger, N. D. Moncrief, M. Goodman, J. Czelusniak
      Pages 16-34

  5. The Function of Calcium Channel

    1. Front Matter

      Pages 37-37
      PDF

    3. Dihydropyridines, G Proteins, and Calcium Channels

      • A. M. Brown, L. Birnbaumer, A. Yatani
      Pages 54-62

    4. Electrophysiology of Dihydropyridine Calcium Agonists

      • M. Bechem, M. Schramm
      Pages 63-70

    11. The Voltage Sensor of Skeletal Muscle Excitation-Contraction Coupling: A Comparison with Ca2+ Channels

      • G. Pizarro, G. Brum, M. Fill, R. Fitts, M. Rodriguez, I. Uribe et al.
      Pages 138-156

  6. The Structure of the Calcium Channel

    1. Front Matter

      Pages 157-157
      PDF

    2. Biochemistry and Molecular Pharmacology of Ca2+ Channels and Ca2+-Channel Blockers

      • J. Barhanin, M. Fosset, M. Hosey, C. Mourre, D. Pauron, J. Qar et al.
      Pages 159-167

    3. The Structure of the Ca2+ Channel: Photoaffinity Labeling and Tissue Distribution

      • H. Glossmann, J. Striessnig, L. Hymel, G. Zernig, H. G. Knaus, H. Schindler
      Pages 168-192

    4. Site-Specific Phosphorylation of the Skeletal Muscle Receptor for Calcium-Channel Blockers by cAMP-Dependent Protein Kinase

      • A. Röhrkasten, H. E. Meyer, T. Schneider, W. Nastainczyk, M. Sieber, H. Jahn et al.
      Pages 193-199

    5. Molecular Properties of Dihydropyridine-Sensitive Calcium Channels from Skeletal Muscle

      • M. J. Seagar, M. Takahashi, W. A. Catterall
      Pages 200-210
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About this book

This is the first book to summarize experimental results from the new, rapidly expanding field of research into the calcium channel in cell membrane. Calcium is an ubiquitous messenger of various cellular functions. Its fundamental role in the regulation of cardiac contractions has long been recognized. Drugs counteracting some actions of calcium ions, namely calcium antagonists, have since become essential to research. In the last decade it has been established that calcium ions reach their target intracellular system by passing through specialized calcium channels in the membrane. Recently improved experimental techniques combined with the discovery of highly specific Ca channel ligands have dramatically enlarged our knowledge of the molecular structure and function of such channels. The contributions by leading world specialists shed new light on both basic science and possible clinical implications for cardiovascular pharmacology, endocrinology and neuropharmacology.
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Keywords

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Editors and Affiliations

  • Department of Physiology, University of Pennsylvania, Philadelphia, USA

    Martin Morad

  • Department of Medicine, Austin Hospital, University of Melbourne, Heidelberg, Australia

    Winifred G. Nayler

  • Bayer AG, Institute of Pharmacology, Wuppertal 1, Germany

    Stanislav Kazda, Matthias Schramm

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Bibliographic Information

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Policies and ethics

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Access via your institution

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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