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Fibrin Sealant in Operative Medicine

Volume 2 Ophthalmology — Neurosurgery

  • Conference proceedings
  • © 1986

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Table of contents (30 papers)

  1. Neurosurgery

Keywords

About this book

Fibrin plays a prominent role in wound healing. It has a hemostatic effect, induces cellular response to wound damage, and, by forming strands to build a matrix, assists in neovascularization and fibroblast proliferation. The concept of using clotting substances from human blood for wound manage­ ment and to achieve hemostasis in bleeding parenchymatous organs can be traced to 1909, when Bergel [1] reported on the hemostatic effect of fibrin powder. In 1915, Grey [3] employed fibrin to control bleeding in neurosurgical operations of the brain. A year later, Harvey [4] used fibrin patches to stop bleeding from parenchy­ matous organs in general surgery. It took more than two decades for this ingenious idea to be rediscovered. In 1940, Young and Medawar [8] reported on experimental nerve anastomosis by sealing. Similarly, Tarlov and Benjamin [7] reunited nerves with plasma clots in 1943. Tarlov improved the results obtained with clot anastomosing of nerves by avoiding tension at the nerve stumps. In 1944, Cronkite et al. [2] reported on an initial series of eight cases in which fibrinogen and thrombin had been used successfully for anchoring skin grafts.

Editors and Affiliations

  • Ludwig-Boltzmann-Instiut für experimentelle Traumatologie, Vienna, Austria

    Günther Schlag, Heinz Redl

Bibliographic Information

  • Book Title: Fibrin Sealant in Operative Medicine

  • Book Subtitle: Volume 2 Ophthalmology — Neurosurgery

  • Editors: Günther Schlag, Heinz Redl

  • DOI: https://doi.org/10.1007/978-3-642-71391-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1986

  • Softcover ISBN: 978-3-540-16828-7Due: 01 August 1986

  • eBook ISBN: 978-3-642-71391-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Illustrations: 62 b/w illustrations

  • Topics: General Surgery, Ophthalmology, Neurosurgery

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

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