Peptides of Poisonous Amanita Mushrooms

1. Front Matter

   Pages I-XIV

   PDF

2. Introduction

   1. Introduction

      • Theodor Wieland

      Pages 1-2

3. Mushrooms Causing Death in Rare Cases

   1. Mushrooms Causing Death in Rare Cases

      • Theodor Wieland

      Pages 3-7

4. Deadly Poisonous Amanita Mushrooms and Their Constituents

   1. Front Matter

      Pages 9-9

      PDF

   2. Toadstools Accumulating Amatoxins

      • Theodor Wieland

      Pages 10-12

   3. Poisoning by Amatoxins

      • Theodor Wieland

      Pages 13-14

   4. Two Centuries of Amanita Research

      • Theodor Wieland

      Pages 15-21

   5. Recognition, Isolation, and Characterization of the Peptide Toxins

      • Theodor Wieland

      Pages 22-46

   6. The Chemistry of the Amatoxins, Phallotoxins and Virotoxins

      • Theodor Wieland

      Pages 47-100

   7. Molecular Pathology of the Amanita Peptides

      • Theodor Wieland

      Pages 101-180

   8. Non-Toxic Peptides from Amanita phalloides

      • Theodor Wieland

      Pages 181-206

   9. Phallolysin

      • Theodor Wieland

      Pages 207-210

   10. Retrospectives and Outlook

       • Theodor Wieland

       Pages 211-212

5. Back Matter

   Pages 213-257

   PDF

During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known ofthe chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects oflife at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macro­ molecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of informa­ tion with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective­ what is known about the field today - and a description of the frontiers of research where our knowledge is increasing steadily.

• biology
• growth
• lipide
• molecular biology
• molecular mechanisms
• nucleic acid
• protein
• proteins
• research

• Max-Planck-Institut für Medizinische Forschung, Heidelberg, Germany

  Theodor Wieland

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