Skip to main content
SpringerLink
Log in
Book cover

Brain Protection

Morphological, Pathophysiological and Clinical Aspects

  • Book
  • © 1983

Overview

Editors:
  1. Klaus Wiedemann

    1. Abteilung für Anaesthesiologie im Zentrum Chirurgie, Universität Heidelberg, Heidelberg 1, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Siegfried Hoyer

    1. Institut für Pathochemie und Allgemeine Neurochemie im Zentrum Pathologie, Universität Heidelberg, Heidelberg 1, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (20 chapters)

  1. Front Matter

    Pages I-XI
    Download chapter PDF

  2. Structural Aspects of Energy Failure States in the Brain

    • H. Kalimo, L. Paljärvi, Y. Olsson, B. K. Siesjö
    Pages 1-11

  3. Morphological Aspects of Brain Protection in Experimentally Induced Hypoxia

    • J. van Reempts, M. Borgers
    Pages 12-24

  4. Survival of Cortical Neurons After Ischemia: Dependency on Severity and Duration

    • G. Rosner, W.-D. Heiss
    Pages 25-30

  5. Membrane Stabilization and Protection of the Ischemic Brain

    • J. Astrup
    Pages 31-37

  6. Recovery from Disturbed Cerebral Ion Homeostasis Following Severe Incomplete Ischemia and Modification by the Metabolic Depressant Drug Etomidate

    • D. Heuser, H. Guggenberger
    Pages 38-44

  7. Comparative Evaluation of Barbiturate and CA++Antagonist Attenuation of Brain Free Fatty Acid Liberation During Global Brain Ischemia

    • G. K. Shiu, E. M. Nemoto, J. P. Nemmer, P. M. Winter
    Pages 45-54

  8. Alterations in Whole Brain Cyclic-AMP and Cerebral Cortex Na-Inducible Cyclic-AMP in Rats During and After Complete Global Ischemia

    • M. R. Lin, E. M. Nemoto, P. D. Kessler
    Pages 55-66

  9. Pathophysiology and Pathobiochemistry of Acute Brain Infarction in the Gerbil: The Influence of Metabolic Inhibition

    • G. Mies, H.-J. Bosma, W. Paschen, K. A. Hossmann
    Pages 67-75

  10. A Dog Model to Evaluate Post-Cardiac Arrest Neurological Outcome

    • A. Mullie, K. Vandevelde, H. van Belle, A. Jagenau, J. van Loon, C. Hermans et al.
    Pages 76-80

  11. Cortical Glucose and Energy Metabolism During Complete Cerebral Ischemia and After Recovery

    • C. Krier, S. Hoyer
    Pages 81-87

  12. Monitoring of Cerebral Ischaemia in Man

    • L. Symon
    Pages 88-94

  13. Clinical Trials of Brain Protection: Problems and Solutions

    • J. D. Miller
    Pages 95-99

  14. Pharmacological Effects in Protective and Resuscitative Models of Brain Hypoxia

    • A. Wauquier, D. Ashton, C. Hermans, G. Clinke
    Pages 100-111

  15. The Clinical Use of Hypnotic Drugs in Head Injury

    • N. M. Dearden, D. G. McDowall
    Pages 112-115

  16. Indications for Cerebral Protection

    • D. Kling, W. Russ, G. Hempelmann
    Pages 116-123

  17. Prophylaxis of Cerebral Ischemic Damage From Vasospasm After Subarachnoid Hemorrhage

    • L. M. Auer
    Pages 124-133

  18. Brain Protection by Barbiturate After Head Injury? Clinical and Experimental Results

    • M. Sold, M. R. Gaab, B. Poch, V. Heller
    Pages 134-145

  19. Thiopentone in the Treatment of Severe Head Injury: Is Raised Intracranial Pressure the Sole Indication for Its Use?

    • K. Wiedemann
    Pages 146-157

  20. Brain Resuscitation in Children: Current Indications and Future Directions

    • D. A. Bruce
    Pages 158-163
Back to top

Keywords

About this book

Significant progress has doubtlessly been made in the field of cere­ bral protection compared to earlier centuries, as recently reviewed by Elisabeth Frost (6). She cites the recommendations for treat­ ment of brain trauma by Areteus, a Greek physician of the second century A. D. He expressed quite modem views with regard to the need for prompt action considering complications that follow even minor symptoms. He advised burr holes for evacuation of hema­ toma in seizures, the use of diuretics and, most interestingly, also hypothermia. German surgeons of the 17th century had little more to offer than prescriptions of which the most effective constituent was alcohol (10). Thus, Sir Astley Cooper was probably the next surgeon to make noteworthy contributions when advising the use of leeches to the temporal artery and other means of bleeding in­ stead of surgical intervention in cases of raised intracranial pressure (loc. cit. 6). Although our knowledge has greatly expanded during the last two decades, extensive discussions have led to only few conclusions. Promising results from animal studies were translated to clinical sit­ uations only to yield controversial and sometimes confusing results. Since the observations of Brierly (5) on ischemic cell damage, im­ proved information on structural aspects, probably even related to concomitant biochemical studies, should allow the validity of thera­ peutic concepts to be verified. Investigations on cerebral ischemia have led to the differentiation of synaptic transmission failure and membrane failure.

Editors and Affiliations

  • Abteilung für Anaesthesiologie im Zentrum Chirurgie, Universität Heidelberg, Heidelberg 1, Germany

    Klaus Wiedemann

  • Institut für Pathochemie und Allgemeine Neurochemie im Zentrum Pathologie, Universität Heidelberg, Heidelberg 1, Germany

    Siegfried Hoyer

Bibliographic Information

  • Book Title: Brain Protection

  • Book Subtitle: Morphological, Pathophysiological and Clinical Aspects

  • Editors: Klaus Wiedemann, Siegfried Hoyer

  • DOI: https://doi.org/10.1007/978-3-642-69175-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1983

  • Softcover ISBN: 978-3-642-69177-5Published: 07 December 2011

  • eBook ISBN: 978-3-642-69175-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XI, 168

  • Topics: Neurology, Neurosciences, Pathology

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

Publish with us

Policies and ethics

Back to top

Search

Navigation