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Current Topics in Microbiology and Immunology

  • Book
  • © 1981

Overview

Editors:
  1. W. Henle

    1. Philadelphia, USA

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  2. P. H. Hofschneider

    1. Martinsried, Germany

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  3. P. Koldovský

    1. Düsseldorf, Germany

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  4. H. Koprowski

    1. Philadelphia, USA

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  5. O. Maaløe

    1. Copenhagen, Denmark

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  6. F. Melchers

    1. Basle, Switzerland

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  7. R. Rott

    1. Gießen, Germany

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  8. H. G. Schweiger

    1. Ladenburg/Heidelberg, Germany

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  9. L. Syruček

    1. Prague, Czech Republic

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  10. P. K. Vogt

    1. Los Angeles, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 91)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-iii
    Download chapter PDF

  2. Genetics of Reovirus

    • Bernard N. Fields
    Pages 1-24

  3. The Transforming Protein of Avian Sarcoma Viruses and Its Homologue in Normal Cells

    • R. L. Erikson
    Pages 25-40

  4. Gene-Specific Probes for Avian Retroviruses

    • Deborah H. Spector
    Pages 41-80

  5. Replication of Herpesvirus DNA

    • Tamar Ben-Porat
    Pages 81-107

  6. The Obese Strain (OS) of Chickens With Spontaneous Autoimmune Thyroiditis: Review of Recent Data

    • G. Wick, R. Boyd, K. Hala, L. De Carvalho, R. Kofler, P. U. Müller et al.
    Pages 109-128

  7. Nucleic Acid Independent Synthesis of Peptides

    • H. Kleinkauf, H. von Döhren
    Pages 129-177

  8. The T-Cell Receptor Problem

    • Peter H. Krammer
    Pages 179-215

  9. Retroviral Gene Expression

    • W. S. Hayward, B. G. Neel
    Pages 217-276
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Keywords

About this book

Several discoveries are noteworthy for allowing us to probe the recesses of the virus­ infected cell and to search for cryptic viral genomes which might provide clues in our studies of cancer etiology or developmental biology. One of the most notable was the dis­ covery of reverse transcriptase. This marked a momentous occasion in the history of molecular biology. Not only did it provide insight into the mechanism of persistence of retroviruses but it also provided us with an enzyme that could synthesize a DNA copy of any RNA. This DNA copy could then be used as a hybridization reagent to search for both complementary DNA and viral-specific RNA. Thus one could follow the course of any viral infection or probe in tumor cells for hidden viral genomes. Second, a great deal of credit must be given to the geneticists who isolated the various deletion mutants in the 'avian retrovirus system and thus provided us with the frrst means of isolating gene-spe­ cific probes. Finally, the laboratories which have mapped the genome have provided us with the framework in which to ask very specific questions with our gene-specific probes. Recently, numerous excellent reviews concerning various aspects of the retroviruses have appeared. In this review I shall not even attempt to present a comprehensive review of retroviruses.

Editors and Affiliations

  • Philadelphia, USA

    W. Henle, H. Koprowski

  • Martinsried, Germany

    P. H. Hofschneider

  • Düsseldorf, Germany

    P. Koldovský

  • Copenhagen, Denmark

    O. Maaløe

  • Basle, Switzerland

    F. Melchers

  • Gießen, Germany

    R. Rott

  • Ladenburg/Heidelberg, Germany

    H. G. Schweiger

  • Prague, Czech Republic

    L. Syruček

  • Los Angeles, USA

    P. K. Vogt

Bibliographic Information

  • Book Title: Current Topics in Microbiology and Immunology

  • Editors: W. Henle, P. H. Hofschneider, P. Koldovský, H. Koprowski, O. Maaløe, F. Melchers, R. Rott, H. G. Schweiger, L. Syruček, … P. K. Vogt

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-68058-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1981

  • Softcover ISBN: 978-3-642-68060-1Published: 16 December 2011

  • eBook ISBN: 978-3-642-68058-8Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IV, 278

  • Topics: Medical Microbiology, Oncology, Allergology, Immunology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma

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