Proteins and Steroids in Early Pregnancy

1. Front Matter

   Pages I-XI

   PDF

2. The Endocrine and Topographic Basis

   1. Proteins and Steroids in Early Pregnancy: General Considerations

      • Peter Karlson

      Pages 1-4

   2. Ultrastructure of Trophoblast-Epithelium Relations During Implantation

      • B. Ove Nilsson

      Pages 5-14

   3. Hormonal Control of Decidualization

      • Koji Yoshinaga

      Pages 15-26

   4. Ultrastructural Observations on Rabbit Luteal Cells and Interstitial Gland Cells During Pseudopregnancy

      • Jozef R. Quatacker

      Pages 27-38

3. The Protein Secretion in Early Pregnancy

   1. Uteroglobin and Other Endometrial Proteins: Biochemistry and Biological Significance in Beginning Pregnancy

      • Henning M. Beier

      Pages 39-71

   2. Localization of Uteroglobin and Related Secretion Proteins in Oviducal, Uterine and Blastocyst Cells

      • Christoph Kirchner

      Pages 73-81

   3. Uteroglobin as a Sensitive Indicator for the Biological Activity of Progestogens

      • Y. Nishino

      Pages 83-87

   4. Prefertilization Progesterone Treatment: Effect on Endometrium Uteroglobin Secretion, and Embryonic Development

      • J. de Visser

      Pages 89-98

   5. Evidence for the Existence of Human Uteroglobin?

      • Carol Lambadarios

      Pages 99-115

4. The Synthetic Machinery and Steroid-Protein Interactions

   1. Studies on Uteroglobin Messenger RNA

      • D. W. Bullock, B. M. Bhatt

      Pages 117-126

   2. Structure and Binding Properties of Rabbit Uteroglobin. Search for a Similar Protein in Human Uterine Fluid

      • Miguel Beato

      Pages 127-140

   3. Steroid Binding to Uteroglobin

      • F. Fridlansky, E. Milgrom

      Pages 141-146

   4. Steroids Receptors in the Genital Tract and the Monitoring of Steroid Hormone Action

      • P. W. Jungblut

      Pages 147-156

5. The Actions and Reactions of the Embryonic System

   1. The Synthesis of Steroids and Proteins in the Pig Blastocyst

      • R. B. Heap, J. E. Gadsby, Catherine Rice, J. S. Perry

      Pages 157-171

   2. Steroid Hormones in Blastocyst Tissue, Uterine Flushings, and Endometrium of Pig, Sheep, and Cow

      • J. E. Gadsby

      Pages 173-182

   3. Proteases of the Blastocyst and of the Uterus

      • H.-W. Denker

      Pages 183-208

   4. Embryo-Associated Plasminogen Activator Prior to and During Implantation in the Mouse

      • Michael I. Sherman

      Pages 209-218

   5. Postfertilization Activation of Stored Maternal mRNA in the One-Cell Mouse Egg

      • Nancy K. Love

      Pages 219-231

   6. The Control of Blastocyst Activity

      • R. J. Aitken

      Pages 233-243

It is about 15 years since the first presentation on uteroglobin was given to a group of developmental biologists, reproductive physiologists, and geneticists who had gathered in November 1966 at Konstanz (Germany). In the following decade so much knowledge was accumulated that a special symposium seemed appropriate. This was organized as a satellite symposium to the International Congress of Endocrinology at Hamburg and brought together 50 scientists at Aachen. These scientists, working in the field of pro­ teins and steroids, in early pregnancy, recognized the impact of what had been reported, and many of them later agreed to contribute to this booN. and thus to present their research d,!ta available until December 1980. The present volume covers a relatively broad spectrum of data and observations which shed some light on preimplantational embryonic life and on the supports and obstacles provided by the maternal organism with respect to final accomplishment of normal im­ plantation and establishment of pregnancy. The book will serve both as a textbook and as a scientific dictionary for Ph.D. students, postdoctoral fellows and advanced scientists working in this area. The course of early pregnancy depends very much on a proper balance of steroid hor­ mones, and the induction of protein synthesis by steroid hormones is one of the well­ known fundamental processes in cellular differentiation and embryonic development.

• embryo
• endocrinology
• hormone
• hormones
• pregnancy
• protein
• steroid
• steroids

• Abteilung Anatomie und Reproduktionsbiologie, Medizinische Fakultät der RWTH Aachen, Aachen, Federal Republic of Germany

  Henning M. Beier

• Institut für Physiologische Chemie I, Medizinische Fakultät der Philipps-Universität, Marburg/Lahn, Federal Republic of Germany

  Peter Karlson

Policies and ethics