Arrestins - Pharmacology and Therapeutic Potential

  • Vsevolod V. Gurevich

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 219)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Eugenia V. Gurevich, Vsevolod V. Gurevich
    Pages 1-12
  3. Arrestins and Regulation of G Protein-Coupled Receptors

    1. Front Matter
      Pages 13-13
    2. Martin J. Lohse, Carsten Hoffmann
      Pages 15-56
    3. Terry Kenakin
      Pages 57-83
    4. Martha E. Sommer, Klaus Peter Hofmann, Martin Heck
      Pages 101-116
    5. Vsevolod V. Gurevich, Xiufeng Song, Sergey A. Vishnivetskiy, Eugenia V. Gurevich
      Pages 133-152
    6. Luis E. Gimenez, Sergey A. Vishnivetskiy, Vsevolod V. Gurevich
      Pages 153-170
  4. Arrestin Interactions with Non-receptor Partners and Roles in Cell Signaling

    1. Front Matter
      Pages 171-171
    2. Xufan Tian, Dong Soo Kang, Jeffrey L. Benovic
      Pages 173-186
    3. Qiuyan Chen, Ya Zhuo, Miyeon Kim, Susan M. Hanson, Derek J. Francis, Sergey A. Vishnivetskiy et al.
      Pages 205-223
    4. Erik G. Strungs, Louis M. Luttrell
      Pages 225-257
    5. Xuanzhi Zhan, Seunghyi Kook, Eugenia V. Gurevich, Vsevolod V. Gurevich
      Pages 259-280
    6. Charles Chavkin, Selena S. Schattauer, Jamie R. Levin
      Pages 281-292
    7. Miranda J. Willis, George S. Baillie
      Pages 293-307
    8. Seunghyi Kook, Vsevolod V. Gurevich, Eugenia V. Gurevich
      Pages 309-339

About this book

Introduction

This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners.

Keywords

G protein-coupled receptors MAP kinases apoptosis arrestin cell signaling proliferation

Editors and affiliations

  • Vsevolod V. Gurevich
    • 1
  1. 1.Professor of PharmacologyVanderbilt University Medical CenterNashvilleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-41199-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 2014
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-41198-4
  • Online ISBN 978-3-642-41199-1
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • About this book
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