Multiple Origins of Sex Differences in Brain

Neuroendocrine Functions and their Pathologies

  • Donald W. Pfaff
  • Yves Christen

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Catherine Dulac, Gregg Christopher
    Pages 35-41
  3. Javier DeFelipe, Lidia Alonso-Nanclares
    Pages 43-57
  4. Francesca Ducci, Laura Bevilacqua, Paola Landi, David Goldman
    Pages 81-102
  5. James M. Swanson, Kimberly D. Lakes, Tim L. Wigal, Nora D. Volkow
    Pages 103-122
  6. Bonnie Auyeung, Simon Baron-Cohen
    Pages 123-137
  7. Phyllis M. Wise, Candice M. Brown, Jodi L. Downs
    Pages 165-178
  8. Back Matter
    Pages 179-181

About this book

Introduction

In theoretical terms, sex differences in brain and behavior offer the possibility of fascinating scientific studies on a range of molecular phenomena such as DNA methylation, chromatin protein modification, non-coding DNA, resulting in important neuroanatomical and neurochemical effects. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples to be discussed today will include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. The meeting will end with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.

Keywords

attention deficit hyperactivity disorders autism chromatin modifications epigenetics fetal hormonal programming genomic imprinting

Editors and affiliations

  • Donald W. Pfaff
    • 1
  • Yves Christen
    • 2
  1. 1., Lab. of Biochem. and Molec. BiologyThe Rockefeller UniversityNew YorkUSA
  2. 2.Fondation IpsenBoulogne BillancourtFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-33721-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-33720-8
  • Online ISBN 978-3-642-33721-5
  • Series Print ISSN 1861-2253
  • About this book
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