Drug Transporters

  • Martin F. Fromm
  • Richard B. Kim

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 201)

Table of contents

  1. Front Matter
    Pages i-x
  2. Anne T. Nies, Hermann Koepsell, Katja Damme, Matthias Schwab
    Pages 105-167
  3. Back Matter
    Pages 449-454

About this book

Introduction

It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

Keywords

Drug-drug Interactions drug elimination drug interactions pharmacogenomics transporters

Editors and affiliations

  • Martin F. Fromm
    • 1
  • Richard B. Kim
    • 2
  1. 1.Inst. Experimentelle und Klinische, Pharmakologie und ToxikologieUniversität Erlangen-NürnbergErlangenGermany
  2. 2.Division of Clinical PharmacologyUniversity of Western OntarioLondonCanada

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-14541-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-14540-7
  • Online ISBN 978-3-642-14541-4
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • About this book
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