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  • © 2009

cGMP: Generators, Effectors and Therapeutic Implications

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 191)

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Table of contents (24 chapters)

  1. Clinical Applications

    1. Modulating cGMP to Treat Lung Diseases

      • Hossein-Ardeschir Ghofrani, Friedrich Grimminger
      Pages 469-483
    2. Modulation of cGMP in Heart Failure: A New Therapeutic Paradigm

      • Guido Boerrigter, Harald Lapp, John C. Burnett
      Pages 485-506
    3. Erectile Dysfunction and Lower Urinary Tract

      • Peter Sandner, Dieter Neuser, Erwin Bischoff
      Pages 507-531
    4. cGMP and cGMP-Dependent Protein Kinase in Platelets and Blood Cells

      • Ulrich Walter, Stepan Gambaryan
      Pages 533-548
  2. Back Matter

    Pages 581-583

About this book

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

Editors and Affiliations

  • Dept. Pharmacology, Monash University, Clayton, Australia

    Harald H. H. W. Schmidt

  • Inst. Pharmakologie und Toxikologie, TU München, München, Germany

    Franz Hofmann

  • Bayer Schering Pharma AG Cardiology Research, Pharma Research Center, Wuppertal, Germany

    Johannes-Peter Stasch

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access