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  • © 2007

Technetium-99m Pharmaceuticals

Preparation and Quality Control in Nuclear Medicine

Editors:

  • Advances made in forty years of radiopharmaceutical development based on Technetium
  • Good manufacturing practice (GMP) and the official quality standards stated for radiopharmaceuticals are part of the quality assurance

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Table of contents (12 chapters)

  1. Front Matter

    Pages I-XX
  2. Part I

    1. Front Matter

      Pages 1-1
    2. Drug Safety

      • I. Zolle
      Pages 3-5
    3. Technetium in Medicine

      • U. Mazzi, R. Schibli, H. -J. Pietzsch, J. -U. Künstler, H. Spies
      Pages 7-58
    4. Quality Assurance of Radiopharmaceuticals

      • T. Bringhammar, I. Zolle
      Pages 67-75
    5. Preparation of Technetium 99mTc Pharmaceuticals

      • J. Mallol, I. Zolle
      Pages 95-98
    6. Quality Control Methods of 99mTc Pharmaceuticals

      • C Decristoforo, I Zolle, F. Rakiás, J Imre, Gy. Jánoki, S. R. Hesslewood
      Pages 123-150
  3. Part II

    1. Front Matter

      Pages 171-171
    2. Monographs of 99mTc Pharmaceuticals

      • I. Zolle, P. O. Bremer, Gy. Jánoki
      Pages 173-337
  4. Back Matter

    Pages 339-345

About this book

Radioactive drug development is a multi-disciplinary task, therefore, in a concerted effort, dedicated scientists and experts from different fields of specialisation have contributed to this book. It is presented in two sections. Section 1 contains basic principles and methods used for analysis, information on the chemistry of technetium and on radiopharmaceuticals labelled with technetium-99m, the characteristics of the 99 Mo/99mTc-generator, of 'kits' and formulations for in-vitro labelling, and special safety aspects for in-vivo labelling of blood cells. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affecting in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients.

Reviews

From the reviews:

"This nicely organized and clearly illustrated book provides an up-to-date resource for radiopharmacists and nuclear medicine physicians who compound and prescribe 99mTc-labeled radiopharmaceuticals. Radiochemists and those concerned with regulatory affairs also will be interested, and the book could be used as a primary text in nuclear medicine training programs. This outstanding book fills a void and is the first compilation of its kind in many years. We recommend it with the highest enthusiasm." (Susan Z. Lever and John R. Lever, Journal of Nuclear Medicine, May, 2009)

Editors and Affiliations

  • Department of Medicinal/Pharmaceutical Chemistry, University of Vienna, Vienna, Austria

    Ilse Zolle

Bibliographic Information

  • Book Title: Technetium-99m Pharmaceuticals

  • Book Subtitle: Preparation and Quality Control in Nuclear Medicine

  • Editors: Ilse Zolle

  • DOI: https://doi.org/10.1007/978-3-540-33990-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2007

  • Hardcover ISBN: 978-3-540-33989-2Published: 07 November 2006

  • Softcover ISBN: 978-3-642-07050-1Published: 14 October 2010

  • eBook ISBN: 978-3-540-33990-8Published: 28 January 2007

  • Edition Number: 1

  • Number of Pages: XX, 345

  • Number of Illustrations: 65 b/w illustrations, 1 illustrations in colour

  • Topics: Imaging / Radiology, Nuclear Medicine

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

Buy it now

Buying options

eBook USD 139.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access