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Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse

Proceedings of an International Workshop on Methods in Clinical Pharmacology Frankfurt, November 14, 1986 / Vorträge und Diskussionen auf einem Internationalen Workshop „Methods in Clinical Pharmacology” Frankfurt, 14. November 1986

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. Norbert Rietbrock

    1. Department of Clinical Pharmacology, University Clinic, Frankfurt am Main, Germany

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  2. Barry G. Woodcock

    1. Clinical Pharmacology, University Clinic, Frankfurt am Main, Germany

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  3. A. Horst Staib

    1. Clinical Pharmacology, University Clinic, Frankfurt am Main, Germany

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  4. Dieter Loew

    1. Clinical Research, MEDICE Pharmaceuticals, Iserlohn and Wuppertal, Germany

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Part of the book series: Methods in clinical pharmacology (MECLPH, volume 7)

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Table of contents (19 papers)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Eröffnung und Themeneinführung

    • N. Rietbrock
    Pages 1-2

  3. Intubation Techniques for the Study of the Absorption of Drugs in Man

    • J. Hirtz
    Pages 3-12

  4. Simultaneous Pharmacokinetic and in vivo Gamma Scintigraphic Monitoring in the Development of an Enprofylline-Sustained Release Tablet

    • J. Ulmius, Z. G. Wagner, O. Borgå, P. Wollmer
    Pages 13-20

  5. In vivo Dissolution and Absorption Kinetics of Sustained-Release Theophylline, Studied with Stable Isotope Methodology

    • J. Caldwell, S. A. Hotchkiss
    Pages 21-27

  6. Course of Development of the HF-Capsule — Variations and Method-Related Typical Findings

    • O. Schuster, B. Hugemann
    Pages 28-38

  7. Evaluation of the Colonic Drug Absorption in Patients with an Artificial Intestinal Stoma and by Colonoscopy in Normal Volunteers

    • K.-H. Antonin, P. Bieck
    Pages 39-52

  8. Theophyllin. Absorption in verschiedenen Darmabschnitten

    • A. H. Staib, D. Loew, S. Harder, J. Kollath, E. H. Graul, O. Schuster et al.
    Pages 53-62

  9. Indication of Absorption of Theophylline from the Large Intestine following Administration of Depot Preparations

    • B. C. Lippold
    Pages 63-66

  10. Impaired Bioavailability of Theophylline Retard Preparations as a Result of pH-dependent Drug Release Rates

    • D. Hellenbrecht, C.-D. Herzfeldt
    Pages 67-68

  11. Lokalisation der Absorption von Furosemid. Befunde und Folgerungen für verschiedene Darreichungsformen

    • D. Loew, A. H. Staib, S. Harder, O. Schuster, E. H. Graul
    Pages 69-75

  12. Absorption of Isosorbide-5-Nitrate from the Gastrointestinal Tract

    • H. Laufen, A. Wildfeuer
    Pages 76-81

  13. Gastrointestinal Absorption of Drugs: Physico-Chemical and Biomathematical Aspects

    • D. Brockmeier, H.-G. Grigoleit
    Pages 82-83

  14. Absorption of Hexobarbital und Caffeine in Patients with Liver Cirrhosis

    • R. Joeres, H. Klinker, G. Hofstetter, W. Zilly, E. Richter
    Pages 84-87

  15. Influence of Absorption Rate on the Metabolic Kinetics of Theophylline

    • S. A. Hotchkiss, J. Caldwell
    Pages 88-92

  16. Metabolism of Fosfestrol by Intestinal Mucosa

    • H. Oelschläger, D. Rothley
    Pages 93-94

  17. Drug Input Rate from the GI-Tract. Michaelis-Menten Kinetics and the Bioavailability of Slow-Release Verapamil and Nifedipine

    • B. G. Woodcock, G. Menke, A. Fischer, H. Köhne, N. Rietbrock
    Pages 95-107

  18. Absorption of Caffeine in Patients with Gastric Stasis and after partial gastrectomy (Billroth II)

    • D. Brachtel, E. Richter
    Pages 108-111

  19. Kurzfassung der round-table-Diskussion

    • D. Loew, A. H. Staib
    Pages 112-115

  20. Schlußwort

    • A. H. Staib
    Pages 115-115
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Keywords

Editors and Affiliations

  • Department of Clinical Pharmacology, University Clinic, Frankfurt am Main, Germany

    Norbert Rietbrock

  • Clinical Pharmacology, University Clinic, Frankfurt am Main, Germany

    Barry G. Woodcock, A. Horst Staib

  • Clinical Research, MEDICE Pharmaceuticals, Iserlohn and Wuppertal, Germany

    Dieter Loew

Bibliographic Information

  • Book Title: Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse

  • Book Subtitle: Proceedings of an International Workshop on Methods in Clinical Pharmacology Frankfurt, November 14, 1986 / Vorträge und Diskussionen auf einem Internationalen Workshop „Methods in Clinical Pharmacology” Frankfurt, 14. November 1986

  • Editors: Norbert Rietbrock, Barry G. Woodcock, A. Horst Staib, Dieter Loew

  • Series Title: Methods in clinical pharmacology

  • DOI: https://doi.org/10.1007/978-3-322-91091-2

  • Publisher: Vieweg+Teubner Verlag Wiesbaden

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Fachmedien Wiesbaden 1987

  • Softcover ISBN: 978-3-528-07944-4Published: 01 January 1987

  • eBook ISBN: 978-3-322-91091-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 119

  • Topics: Gastroenterology, Medicine/Public Health, general

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

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